Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
MDA-MB-157
TNBC
Basal B
Sirolimus
MTOR
MTOR
0.00213
uM
7879.068
1.0495 1.0533 1.8348
MDA-MB-157
TNBC
Basal B
Sirolimus
MTOR
MTOR
0.0107
uM
7879.068
1.0642 1.0690 1.8348
MDA-MB-157
TNBC
Basal B
Sirolimus
MTOR
MTOR
0.0533
uM
7879.068
0.9473 0.9418 1.8348
MDA-MB-157
TNBC
Basal B
Sirolimus
MTOR
MTOR
0.267
uM
7879.068
0.9968 0.9965 1.8348
MDA-MB-157
TNBC
Basal B
Sirolimus
MTOR
MTOR
1.33
uM
7879.068
0.9909 0.9901 1.8348
MDA-MB-157
TNBC
Basal B
Sirolimus
MTOR
MTOR
6.67
uM
7879.068
1.0242 1.0263 1.8348
MDA-MB-157
TNBC
Basal B
Sirolimus
MTOR
MTOR
33.3
uM
7879.068
0.9650 0.9616 1.8348
MDA-MB-157
TNBC
Basal B
Sirolimus
MTOR
MTOR
167
uM
7879.068
0.8608 0.8431 1.8348
MDA-MB-175-VII
HR+
Luminal
Sirolimus
MTOR
MTOR
0.000427
uM
7499.068
0.9587 0.8951 0.7825
MDA-MB-175-VII
HR+
Luminal
Sirolimus
MTOR
MTOR
0.00213
uM
7499.068
0.8035 0.5122 0.7825
MDA-MB-175-VII
HR+
Luminal
Sirolimus
MTOR
MTOR
0.0107
uM
7499.068
0.7480 0.3799 0.7825
MDA-MB-175-VII
HR+
Luminal
Sirolimus
MTOR
MTOR
0.0533
uM
7499.068
0.6013 0.0441 0.7825
MDA-MB-175-VII
HR+
Luminal
Sirolimus
MTOR
MTOR
0.267
uM
7499.068
0.5998 0.0406 0.7825
MDA-MB-175-VII
HR+
Luminal
Sirolimus
MTOR
MTOR
1.33
uM
7499.068
0.5968 0.0341 0.7825
MDA-MB-175-VII
HR+
Luminal
Sirolimus
MTOR
MTOR
6.67
uM
7499.068
0.6196 0.0847 0.7825
MDA-MB-175-VII
HR+
Luminal
Sirolimus
MTOR
MTOR
33.3
uM
7499.068
0.5712 -0.0222 0.7825
MDA-MB-175-VII
HR+
Luminal
Sirolimus
MTOR
MTOR
167
uM
7499.068
0.5942 0.0283 0.7825
MDA-MB-175-VII
HR+
Luminal
Sirolimus
MTOR
MTOR
0.0000853
uM
7500.069
1.0559 1.1465 0.7701
MDA-MB-175-VII
HR+
Luminal
Sirolimus
MTOR
MTOR
0.000427
uM
7500.069
1.0097 1.0252 0.7701
MDA-MB-175-VII
HR+
Luminal
Sirolimus
MTOR
MTOR
0.00213
uM
7500.069
0.8547 0.6312 0.7701
MDA-MB-175-VII
HR+
Luminal
Sirolimus
MTOR
MTOR
0.0107
uM
7500.069
0.7780 0.4438 0.7701
MDA-MB-175-VII
HR+
Luminal
Sirolimus
MTOR
MTOR
0.0533
uM
7500.069
0.8005 0.4981 0.7701
MDA-MB-175-VII
HR+
Luminal
Sirolimus
MTOR
MTOR
0.267
uM
7500.069
0.7845 0.4593 0.7701
MDA-MB-175-VII
HR+
Luminal
Sirolimus
MTOR
MTOR
1.33
uM
7500.069
0.7997 0.4962 0.7701
MDA-MB-175-VII
HR+
Luminal
Sirolimus
MTOR
MTOR
6.67
uM
7500.069
0.7636 0.4090 0.7701