Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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MDA-MB-157 | TNBC | Basal B | Sirolimus | MTOR | MTOR | 0.00213 | uM | 7879.068 | 1.0495 | 1.0533 | 1.8348 | |
MDA-MB-157 | TNBC | Basal B | Sirolimus | MTOR | MTOR | 0.0107 | uM | 7879.068 | 1.0642 | 1.0690 | 1.8348 | |
MDA-MB-157 | TNBC | Basal B | Sirolimus | MTOR | MTOR | 0.0533 | uM | 7879.068 | 0.9473 | 0.9418 | 1.8348 | |
MDA-MB-157 | TNBC | Basal B | Sirolimus | MTOR | MTOR | 0.267 | uM | 7879.068 | 0.9968 | 0.9965 | 1.8348 | |
MDA-MB-157 | TNBC | Basal B | Sirolimus | MTOR | MTOR | 1.33 | uM | 7879.068 | 0.9909 | 0.9901 | 1.8348 | |
MDA-MB-157 | TNBC | Basal B | Sirolimus | MTOR | MTOR | 6.67 | uM | 7879.068 | 1.0242 | 1.0263 | 1.8348 | |
MDA-MB-157 | TNBC | Basal B | Sirolimus | MTOR | MTOR | 33.3 | uM | 7879.068 | 0.9650 | 0.9616 | 1.8348 | |
MDA-MB-157 | TNBC | Basal B | Sirolimus | MTOR | MTOR | 167 | uM | 7879.068 | 0.8608 | 0.8431 | 1.8348 | |
MDA-MB-175-VII | HR+ | Luminal | Sirolimus | MTOR | MTOR | 0.000427 | uM | 7499.068 | 0.9587 | 0.8951 | 0.7825 | |
MDA-MB-175-VII | HR+ | Luminal | Sirolimus | MTOR | MTOR | 0.00213 | uM | 7499.068 | 0.8035 | 0.5122 | 0.7825 | |
MDA-MB-175-VII | HR+ | Luminal | Sirolimus | MTOR | MTOR | 0.0107 | uM | 7499.068 | 0.7480 | 0.3799 | 0.7825 | |
MDA-MB-175-VII | HR+ | Luminal | Sirolimus | MTOR | MTOR | 0.0533 | uM | 7499.068 | 0.6013 | 0.0441 | 0.7825 | |
MDA-MB-175-VII | HR+ | Luminal | Sirolimus | MTOR | MTOR | 0.267 | uM | 7499.068 | 0.5998 | 0.0406 | 0.7825 | |
MDA-MB-175-VII | HR+ | Luminal | Sirolimus | MTOR | MTOR | 1.33 | uM | 7499.068 | 0.5968 | 0.0341 | 0.7825 | |
MDA-MB-175-VII | HR+ | Luminal | Sirolimus | MTOR | MTOR | 6.67 | uM | 7499.068 | 0.6196 | 0.0847 | 0.7825 | |
MDA-MB-175-VII | HR+ | Luminal | Sirolimus | MTOR | MTOR | 33.3 | uM | 7499.068 | 0.5712 | -0.0222 | 0.7825 | |
MDA-MB-175-VII | HR+ | Luminal | Sirolimus | MTOR | MTOR | 167 | uM | 7499.068 | 0.5942 | 0.0283 | 0.7825 | |
MDA-MB-175-VII | HR+ | Luminal | Sirolimus | MTOR | MTOR | 0.0000853 | uM | 7500.069 | 1.0559 | 1.1465 | 0.7701 | |
MDA-MB-175-VII | HR+ | Luminal | Sirolimus | MTOR | MTOR | 0.000427 | uM | 7500.069 | 1.0097 | 1.0252 | 0.7701 | |
MDA-MB-175-VII | HR+ | Luminal | Sirolimus | MTOR | MTOR | 0.00213 | uM | 7500.069 | 0.8547 | 0.6312 | 0.7701 | |
MDA-MB-175-VII | HR+ | Luminal | Sirolimus | MTOR | MTOR | 0.0107 | uM | 7500.069 | 0.7780 | 0.4438 | 0.7701 | |
MDA-MB-175-VII | HR+ | Luminal | Sirolimus | MTOR | MTOR | 0.0533 | uM | 7500.069 | 0.8005 | 0.4981 | 0.7701 | |
MDA-MB-175-VII | HR+ | Luminal | Sirolimus | MTOR | MTOR | 0.267 | uM | 7500.069 | 0.7845 | 0.4593 | 0.7701 | |
MDA-MB-175-VII | HR+ | Luminal | Sirolimus | MTOR | MTOR | 1.33 | uM | 7500.069 | 0.7997 | 0.4962 | 0.7701 | |
MDA-MB-175-VII | HR+ | Luminal | Sirolimus | MTOR | MTOR | 6.67 | uM | 7500.069 | 0.7636 | 0.4090 | 0.7701 |