Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1143 | TNBC | Basal A | Taxol | TUBB | TUBB | 33.3 | uM | 9233.002 | 0.2775 | -0.4917 | 0.9358 | |
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0000853 | uM | 7811.002 | 0.9945 | 0.9779 | 0.4929 | |
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.000427 | uM | 7811.002 | 0.9188 | 0.6843 | 0.4929 | |
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.00213 | uM | 7811.002 | 0.9707 | 0.8829 | 0.4929 | |
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0107 | uM | 7811.002 | 0.7099 | -0.0019 | 0.4929 | |
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0533 | uM | 7811.002 | 0.1312 | -0.9675 | 0.4929 | |
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.267 | uM | 7811.002 | 0.0793 | -0.9883 | 0.4929 | |
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 1.33 | uM | 7811.002 | 0.0786 | -0.9885 | 0.4929 | |
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 6.67 | uM | 7811.002 | 0.0741 | -0.9898 | 0.4929 | |
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 33.3 | uM | 7811.002 | 0.0767 | -0.9891 | 0.4929 | |
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0000853 | uM | 7812.002 | 1.0980 | 1.1821 | 1.0730 | |
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.000427 | uM | 7812.002 | 1.0282 | 1.0525 | 1.0730 | |
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.00213 | uM | 7812.002 | 1.0714 | 1.1327 | 1.0730 | |
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0107 | uM | 7812.002 | 0.4153 | -0.1181 | 1.0730 | |
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0533 | uM | 7812.002 | 0.0812 | -0.8073 | 1.0730 | |
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.267 | uM | 7812.002 | 0.0869 | -0.7947 | 1.0730 | |
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 1.33 | uM | 7812.002 | 0.0825 | -0.8046 | 1.0730 | |
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 6.67 | uM | 7812.002 | 0.0836 | -0.8021 | 1.0730 | |
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 33.3 | uM | 7812.002 | 0.0797 | -0.8107 | 1.0730 | |
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0000853 | uM | 9244.002 | 1.2771 | 2.1995 | 0.5206 | |
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.000427 | uM | 9244.002 | 0.9783 | 0.9173 | 0.5206 | |
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.00213 | uM | 9244.002 | 1.1291 | 1.5253 | 0.5206 | |
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0107 | uM | 9244.002 | 0.5305 | -0.4081 | 0.5206 | |
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.0533 | uM | 9244.002 | 0.0450 | -0.9948 | 0.5206 | |
| HCC1187 | TNBC | Basal A | Taxol | TUBB | TUBB | 0.267 | uM | 9244.002 | 0.0473 | -0.9943 | 0.5206 |