Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
ZR75B	HR+	Luminal	Sigma A6730	AKT	AKT	0.107	uM	11939.158	0.9223	0.9084	1.7251
ZR75B	HR+	Luminal	Sigma A6730	AKT	AKT	0.533	uM	11939.158	0.7374	0.6762	1.7251
ZR75B	HR+	Luminal	Sigma A6730	AKT	AKT	2.67	uM	11939.158	0.4863	0.3169	1.7251
ZR75B	HR+	Luminal	Sigma A6730	AKT	AKT	13.3	uM	11939.158	0.3210	0.0350	1.7251
ZR75B	HR+	Luminal	Sigma A6730	AKT	AKT	66.7	uM	11939.158	0.1079	-0.4497	1.7251
184A1	NM	Basal	Sirolimus	MTOR	MTOR	0.000427	uM	7787.068	0.7543	0.4893	0.9562
184A1	NM	Basal	Sirolimus	MTOR	MTOR	0.00213	uM	7787.068	0.9348	0.8638	0.9562
184A1	NM	Basal	Sirolimus	MTOR	MTOR	0.0107	uM	7787.068	0.8539	0.6955	0.9562
184A1	NM	Basal	Sirolimus	MTOR	MTOR	0.0533	uM	7787.068	0.5924	0.1566	0.9562
184A1	NM	Basal	Sirolimus	MTOR	MTOR	0.267	uM	7787.068	0.7085	0.3948	0.9562
184A1	NM	Basal	Sirolimus	MTOR	MTOR	1.33	uM	7787.068	0.6702	0.3160	0.9562
184A1	NM	Basal	Sirolimus	MTOR	MTOR	6.67	uM	7787.068	0.7884	0.5597	0.9562
184A1	NM	Basal	Sirolimus	MTOR	MTOR	33.3	uM	7787.068	0.6388	0.2516	0.9562
184A1	NM	Basal	Sirolimus	MTOR	MTOR	167	uM	7787.068	0.3768	-0.2794	0.9562
184B5	NM	Basal	Sirolimus	MTOR	MTOR	0.0000853	uM	5896.069	0.9716	0.9632	1.5507
184B5	NM	Basal	Sirolimus	MTOR	MTOR	0.000427	uM	5896.069	1.0456	1.0584	1.5507
184B5	NM	Basal	Sirolimus	MTOR	MTOR	0.00213	uM	5896.069	0.9434	0.9262	1.5507
184B5	NM	Basal	Sirolimus	MTOR	MTOR	0.0107	uM	5896.069	0.8913	0.8569	1.5507
184B5	NM	Basal	Sirolimus	MTOR	MTOR	0.0533	uM	5896.069	0.7881	0.7152	1.5507
184B5	NM	Basal	Sirolimus	MTOR	MTOR	0.267	uM	5896.069	0.8262	0.7684	1.5507
184B5	NM	Basal	Sirolimus	MTOR	MTOR	1.33	uM	5896.069	0.8262	0.7683	1.5507
184B5	NM	Basal	Sirolimus	MTOR	MTOR	6.67	uM	5896.069	0.8346	0.7798	1.5507
184B5	NM	Basal	Sirolimus	MTOR	MTOR	33.3	uM	5896.069	0.8315	0.7756	1.5507
184B5	NM	Basal	Sirolimus	MTOR	MTOR	0.000427	uM	7789.068	0.8236	0.0944	0.3219
184B5	NM	Basal	Sirolimus	MTOR	MTOR	0.00213	uM	7789.068	1.0158	1.1000	0.3219

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)