Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MDA-MB-361	HER2amp	Luminal	Sigma A6730	AKT	AKT	2.67	uM	10999.153	0.6314	-0.0009	0.6626
MDA-MB-361	HER2amp	Luminal	Sigma A6730	AKT	AKT	13.3	uM	10999.153	0.3390	-0.6091	0.6626
MDA-MB-361	HER2amp	Luminal	Sigma A6730	AKT	AKT	66.7	uM	10999.153	0.0442	-0.9819	0.6626
MDA-MB-361	HER2amp	Luminal	Sigma A6730	AKT	AKT	0.000171	uM	12379.165	0.9741	0.8576	0.3550
MDA-MB-361	HER2amp	Luminal	Sigma A6730	AKT	AKT	0.000853	uM	12379.165	0.9870	0.9276	0.3550
MDA-MB-361	HER2amp	Luminal	Sigma A6730	AKT	AKT	0.00427	uM	12379.165	0.9543	0.7530	0.3550
MDA-MB-361	HER2amp	Luminal	Sigma A6730	AKT	AKT	0.0213	uM	12379.165	0.9789	0.8831	0.3550
MDA-MB-361	HER2amp	Luminal	Sigma A6730	AKT	AKT	0.107	uM	12379.165	1.0013	1.0073	0.3550
MDA-MB-361	HER2amp	Luminal	Sigma A6730	AKT	AKT	0.533	uM	12379.165	0.9502	0.7318	0.3550
MDA-MB-361	HER2amp	Luminal	Sigma A6730	AKT	AKT	2.67	uM	12379.165	0.7347	-0.1607	0.3550
MDA-MB-361	HER2amp	Luminal	Sigma A6730	AKT	AKT	13.3	uM	12379.165	0.3584	-0.8889	0.3550
MDA-MB-361	HER2amp	Luminal	Sigma A6730	AKT	AKT	66.7	uM	12379.165	0.0214	-1.0000	0.3550
MDA-MB-415	HR+	Luminal	Sigma A6730	AKT	AKT	0.000171	uM	10938.153	1.3056	2.7575	0.4228
MDA-MB-415	HR+	Luminal	Sigma A6730	AKT	AKT	0.000853	uM	10938.153	1.3507	3.0722	0.4228
MDA-MB-415	HR+	Luminal	Sigma A6730	AKT	AKT	0.00427	uM	10938.153	1.4468	3.7910	0.4228
MDA-MB-415	HR+	Luminal	Sigma A6730	AKT	AKT	0.0213	uM	10938.153	1.3385	2.9859	0.4228
MDA-MB-415	HR+	Luminal	Sigma A6730	AKT	AKT	0.107	uM	10938.153	0.8607	0.4028	0.4228
MDA-MB-415	HR+	Luminal	Sigma A6730	AKT	AKT	0.533	uM	10938.153	1.3114	2.7972	0.4228
MDA-MB-415	HR+	Luminal	Sigma A6730	AKT	AKT	2.67	uM	10938.153	1.2375	2.3104	0.4228
MDA-MB-415	HR+	Luminal	Sigma A6730	AKT	AKT	13.3	uM	10938.153	0.5009	-0.6102	0.4228
MDA-MB-415	HR+	Luminal	Sigma A6730	AKT	AKT	66.7	uM	10938.153	0.0270	-0.9996	0.4228
MDA-MB-415	HR+	Luminal	Sigma A6730	AKT	AKT	0.000171	uM	12333.165	0.9155	0.7349	0.6207
MDA-MB-415	HR+	Luminal	Sigma A6730	AKT	AKT	0.000853	uM	12333.165	0.9068	0.7084	0.6207
MDA-MB-415	HR+	Luminal	Sigma A6730	AKT	AKT	0.00427	uM	12333.165	0.8915	0.6621	0.6207
MDA-MB-415	HR+	Luminal	Sigma A6730	AKT	AKT	0.0213	uM	12333.165	0.8962	0.6762	0.6207

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)