Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 7467.067 | 0.9626 | 0.9433 | 1.3252 | |
| HCC3153 | TNBC | Basal A | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 7467.067 | 0.9783 | 0.9671 | 1.3252 | |
| HCC3153 | TNBC | Basal A | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 7467.067 | 0.8655 | 0.7935 | 1.3252 | |
| HCC3153 | TNBC | Basal A | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 7467.067 | 0.0119 | -0.9294 | 1.3252 | |
| HCC3153 | TNBC | Basal A | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 7467.067 | 0.0026 | -0.9776 | 1.3252 | |
| HCC38 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 7468.067 | 0.9589 | 0.9402 | 1.3847 | |
| HCC38 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 7468.067 | 1.0022 | 1.0032 | 1.3847 | |
| HCC38 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 7468.067 | 1.0064 | 1.0093 | 1.3847 | |
| HCC38 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 7468.067 | 1.0070 | 1.0101 | 1.3847 | |
| HCC38 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 7468.067 | 1.0525 | 1.0753 | 1.3847 | |
| HCC38 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 7468.067 | 1.0353 | 1.0507 | 1.3847 | |
| HCC38 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 7468.067 | 0.3433 | -0.0758 | 1.3847 | |
| HCC38 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 7468.067 | 0.0093 | -0.9316 | 1.3847 | |
| HCC38 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 7468.067 | 0.0013 | -0.9839 | 1.3847 | |
| HCC38 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 7469.067 | 0.9411 | 0.9420 | 2.0639 | |
| HCC38 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 7469.067 | 0.9531 | 0.9540 | 2.0639 | |
| HCC38 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 7469.067 | 0.9337 | 0.9346 | 2.0639 | |
| HCC38 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 7469.067 | 0.9772 | 0.9778 | 2.0639 | |
| HCC38 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 7469.067 | 1.0160 | 1.0154 | 2.0639 | |
| HCC38 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 7469.067 | 0.9767 | 0.9773 | 2.0639 | |
| HCC38 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 7469.067 | 0.3309 | 0.1703 | 2.0639 | |
| HCC38 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 7469.067 | 0.0065 | -0.8262 | 2.0639 | |
| HCC38 | TNBC | Basal B | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 7469.067 | 0.0013 | -0.9189 | 2.0639 | |
| HCC70 | TNBC | Basal A | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 7470.067 | 1.0133 | 1.0247 | 1.0774 | |
| HCC70 | TNBC | Basal A | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 7470.067 | 1.0082 | 1.0152 | 1.0774 |