Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMA-1 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 5911.067 | 0.8412 | 0.6834 | 1.0037 | |
| CAMA-1 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 5911.067 | 0.0082 | -0.9833 | 1.0037 | |
| CAMA-1 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 5911.067 | 0.0045 | -0.9909 | 1.0037 | |
| CAMA-1 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 5912.067 | 0.9594 | 0.9306 | 1.1725 | |
| CAMA-1 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 5912.067 | 0.9521 | 0.9180 | 1.1725 | |
| CAMA-1 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 5912.067 | 0.9678 | 0.9449 | 1.1725 | |
| CAMA-1 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 5912.067 | 0.9702 | 0.9491 | 1.1725 | |
| CAMA-1 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 5912.067 | 0.9649 | 0.9399 | 1.1725 | |
| CAMA-1 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 5912.067 | 0.9461 | 0.9077 | 1.1725 | |
| CAMA-1 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 5912.067 | 0.8611 | 0.7606 | 1.1725 | |
| CAMA-1 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 5912.067 | 0.0115 | -0.9557 | 1.1725 | |
| CAMA-1 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 5912.067 | 0.0061 | -0.9743 | 1.1725 | |
| HBL-100 | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 7429.067 | 1.0646 | 1.0573 | 2.2169 | |
| HBL-100 | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 7429.067 | 1.0659 | 1.0584 | 2.2169 | |
| HBL-100 | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 7429.067 | 1.0342 | 1.0306 | 2.2169 | |
| HBL-100 | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 7429.067 | 1.0183 | 1.0164 | 2.2169 | |
| HBL-100 | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 7429.067 | 1.0960 | 1.0844 | 2.2169 | |
| HBL-100 | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 7429.067 | 1.0158 | 1.0142 | 2.2169 | |
| HBL-100 | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 7429.067 | 0.2745 | 0.1163 | 2.2169 | |
| HBL-100 | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 7429.067 | 0.0056 | -0.8075 | 2.2169 | |
| HBL-100 | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 7429.067 | 0.0012 | -0.9039 | 2.2169 | |
| HCC1143 | TNBC | Basal A | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 7430.067 | 1.0510 | 1.0522 | 1.9308 | |
| HCC1143 | TNBC | Basal A | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 7430.067 | 1.0231 | 1.0238 | 1.9308 | |
| HCC1143 | TNBC | Basal A | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 7430.067 | 0.9913 | 0.9909 | 1.9308 | |
| HCC1143 | TNBC | Basal A | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 7430.067 | 1.0082 | 1.0085 | 1.9308 |