Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 10580.144 | 0.8873 | 0.7387 | 0.8541 | |
| UACC-812 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 10580.144 | 0.9765 | 0.9451 | 0.8541 | |
| UACC-812 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 10580.144 | 0.9213 | 0.8170 | 0.8541 | |
| UACC-812 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 4 | uM | 10580.144 | 0.9654 | 0.9193 | 0.8541 | |
| UACC-812 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 20 | uM | 10580.144 | 0.8929 | 0.7516 | 0.8541 | |
| UACC-812 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 100 | uM | 10580.144 | 0.9406 | 0.8616 | 0.8541 | |
| UACC-812 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 10754.144 | 1.1839 | 1.4458 | 0.8390 | |
| UACC-812 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 10754.144 | 0.9521 | 0.8862 | 0.8390 | |
| UACC-812 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 10754.144 | 1.0850 | 1.2042 | 0.8390 | |
| UACC-812 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 10754.144 | 0.9381 | 0.8533 | 0.8390 | |
| UACC-812 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 10754.144 | 1.0225 | 1.0537 | 0.8390 | |
| UACC-812 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 10754.144 | 1.0789 | 1.1895 | 0.8390 | |
| UACC-812 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 4 | uM | 10754.144 | 0.7675 | 0.4591 | 0.8390 | |
| UACC-812 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 20 | uM | 10754.144 | 0.5436 | -0.0329 | 0.8390 | |
| UACC-812 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 100 | uM | 10754.144 | 0.1921 | -0.7200 | 0.8390 | |
| UACC-812 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 11938.144 | 0.9546 | 0.8608 | 0.6445 | |
| UACC-812 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 11938.144 | 0.8562 | 0.5717 | 0.6445 | |
| UACC-812 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 11938.144 | 0.9251 | 0.7725 | 0.6445 | |
| UACC-812 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 11938.144 | 0.8187 | 0.4662 | 0.6445 | |
| UACC-812 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 11938.144 | 0.9524 | 0.8542 | 0.6445 | |
| UACC-812 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 11938.144 | 0.9679 | 0.9013 | 0.6445 | |
| UACC-812 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 4 | uM | 11938.144 | 0.8638 | 0.5935 | 0.6445 | |
| UACC-812 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 20 | uM | 11938.144 | 0.9564 | 0.8664 | 0.6445 | |
| UACC-812 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 100 | uM | 11938.144 | 0.8727 | 0.6191 | 0.6445 | |
| ZR-75-1 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 11660.144 | 1.0269 | 1.0523 | 1.0279 |