Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ZR-75-1 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 11660.144 | 0.9373 | 0.8778 | 1.0279 | |
| ZR-75-1 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 11660.144 | 0.9686 | 0.9390 | 1.0279 | |
| ZR-75-1 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 11660.144 | 0.9731 | 0.9477 | 1.0279 | |
| ZR-75-1 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 11660.144 | 1.0203 | 1.0395 | 1.0279 | |
| ZR-75-1 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 11660.144 | 0.9823 | 0.9656 | 1.0279 | |
| ZR-75-1 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 4 | uM | 11660.144 | 0.9852 | 0.9713 | 1.0279 | |
| ZR-75-1 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 20 | uM | 11660.144 | 0.9178 | 0.8398 | 1.0279 | |
| ZR-75-1 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 100 | uM | 11660.144 | 0.7643 | 0.5398 | 1.0279 | |
| ZR-75-1 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.000427 | uM | 12003.168 | 0.9134 | 0.8468 | 1.1370 | |
| ZR-75-1 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.00213 | uM | 12003.168 | 0.8862 | 0.7983 | 1.1370 | |
| ZR-75-1 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.0107 | uM | 12003.168 | 0.9486 | 0.9092 | 1.1370 | |
| ZR-75-1 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.0533 | uM | 12003.168 | 0.9579 | 0.9258 | 1.1370 | |
| ZR-75-1 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.267 | uM | 12003.168 | 0.9155 | 0.8505 | 1.1370 | |
| ZR-75-1 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 1.33 | uM | 12003.168 | 0.9882 | 0.9793 | 1.1370 | |
| ZR-75-1 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 6.67 | uM | 12003.168 | 0.9391 | 0.8925 | 1.1370 | |
| ZR-75-1 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 33.3 | uM | 12003.168 | 0.8957 | 0.8153 | 1.1370 | |
| ZR-75-1 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 167 | uM | 12003.168 | 0.8774 | 0.7827 | 1.1370 | |
| ZR75B | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 11939.144 | 0.9840 | 0.9805 | 1.6446 | |
| ZR75B | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 11939.144 | 0.9343 | 0.9190 | 1.6446 | |
| ZR75B | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 11939.144 | 0.9646 | 0.9566 | 1.6446 | |
| ZR75B | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 11939.144 | 0.9814 | 0.9773 | 1.6446 | |
| ZR75B | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 11939.144 | 0.9748 | 0.9692 | 1.6446 | |
| ZR75B | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 11939.144 | 0.9275 | 0.9105 | 1.6446 | |
| ZR75B | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 4 | uM | 11939.144 | 1.0113 | 1.0137 | 1.6446 | |
| ZR75B | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 20 | uM | 11939.144 | 0.8303 | 0.7862 | 1.6446 |