Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-134-VI | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 12206.144 | 0.9920 | 0.9837 | 0.9811 | |
| MDA-MB-134-VI | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 4 | uM | 12206.144 | 0.9365 | 0.8707 | 0.9811 | |
| MDA-MB-134-VI | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 20 | uM | 12206.144 | 0.9228 | 0.8427 | 0.9811 | |
| MDA-MB-134-VI | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 100 | uM | 12206.144 | 0.8839 | 0.7635 | 0.9811 | |
| MDA-MB-157 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.000427 | uM | 12594.168 | 1.0347 | 1.0544 | 1.2703 | |
| MDA-MB-157 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.00213 | uM | 12594.168 | 1.0256 | 1.0403 | 1.2703 | |
| MDA-MB-157 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.0107 | uM | 12594.168 | 0.9768 | 0.9633 | 1.2703 | |
| MDA-MB-157 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.0533 | uM | 12594.168 | 0.9795 | 0.9677 | 1.2703 | |
| MDA-MB-157 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.267 | uM | 12594.168 | 1.0391 | 1.0613 | 1.2703 | |
| MDA-MB-157 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 1.33 | uM | 12594.168 | 0.9865 | 0.9787 | 1.2703 | |
| MDA-MB-157 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 6.67 | uM | 12594.168 | 0.9964 | 0.9943 | 1.2703 | |
| MDA-MB-157 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 33.3 | uM | 12594.168 | 0.9312 | 0.8909 | 1.2703 | |
| MDA-MB-157 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 167 | uM | 12594.168 | 0.9067 | 0.8515 | 1.2703 | |
| MDA-MB-175-VII | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 10642.144 | 0.9816 | 0.9439 | 0.6510 | |
| MDA-MB-175-VII | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 10642.144 | 0.9343 | 0.8016 | 0.6510 | |
| MDA-MB-175-VII | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 10642.144 | 0.9650 | 0.8935 | 0.6510 | |
| MDA-MB-175-VII | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 10642.144 | 0.9235 | 0.7698 | 0.6510 | |
| MDA-MB-175-VII | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 10642.144 | 0.9912 | 0.9731 | 0.6510 | |
| MDA-MB-175-VII | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 10642.144 | 0.9796 | 0.9376 | 0.6510 | |
| MDA-MB-175-VII | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 4 | uM | 10642.144 | 0.9288 | 0.7856 | 0.6510 | |
| MDA-MB-175-VII | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 20 | uM | 10642.144 | 0.9230 | 0.7684 | 0.6510 | |
| MDA-MB-175-VII | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 100 | uM | 10642.144 | 0.9663 | 0.8974 | 0.6510 | |
| MDA-MB-175-VII | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 10818.144 | 1.0284 | 1.1172 | 0.4912 | |
| MDA-MB-175-VII | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 10818.144 | 0.9209 | 0.6910 | 0.4912 | |
| MDA-MB-175-VII | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 10818.144 | 0.9937 | 0.9743 | 0.4912 |