Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 11852.144 | 1.1236 | 1.1895 | 1.2876 | |
| SUM52PE | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 4 | uM | 11852.144 | 1.0145 | 1.0225 | 1.2876 | |
| SUM52PE | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 20 | uM | 11852.144 | 0.9432 | 0.9112 | 1.2876 | |
| SUM52PE | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 100 | uM | 11852.144 | 0.7507 | 0.6006 | 1.2876 | |
| T47D | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 10939.144 | 0.9611 | 0.9542 | 1.7115 | |
| T47D | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 10939.144 | 0.9354 | 0.9235 | 1.7115 | |
| T47D | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 10939.144 | 0.9583 | 0.9509 | 1.7115 | |
| T47D | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 10939.144 | 0.9496 | 0.9405 | 1.7115 | |
| T47D | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 10939.144 | 0.9302 | 0.9172 | 1.7115 | |
| T47D | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 10939.144 | 0.9741 | 0.9695 | 1.7115 | |
| T47D | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 4 | uM | 10939.144 | 0.9678 | 0.9621 | 1.7115 | |
| T47D | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 20 | uM | 10939.144 | 0.9294 | 0.9162 | 1.7115 | |
| T47D | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 100 | uM | 10939.144 | 0.7531 | 0.6947 | 1.7115 | |
| T47DKBLUC | Unknown | Unknown | SB-3CT | MMP2/9 | MMP | 0.000427 | uM | 12608.168 | 0.9933 | 0.9872 | 1.0486 | |
| T47DKBLUC | Unknown | Unknown | SB-3CT | MMP2/9 | MMP | 0.00213 | uM | 12608.168 | 0.9688 | 0.9405 | 1.0486 | |
| T47DKBLUC | Unknown | Unknown | SB-3CT | MMP2/9 | MMP | 0.0107 | uM | 12608.168 | 1.0031 | 1.0058 | 1.0486 | |
| T47DKBLUC | Unknown | Unknown | SB-3CT | MMP2/9 | MMP | 0.0533 | uM | 12608.168 | 0.9796 | 0.9610 | 1.0486 | |
| T47DKBLUC | Unknown | Unknown | SB-3CT | MMP2/9 | MMP | 0.267 | uM | 12608.168 | 0.9816 | 0.9649 | 1.0486 | |
| T47DKBLUC | Unknown | Unknown | SB-3CT | MMP2/9 | MMP | 1.33 | uM | 12608.168 | 0.9837 | 0.9689 | 1.0486 | |
| T47DKBLUC | Unknown | Unknown | SB-3CT | MMP2/9 | MMP | 6.67 | uM | 12608.168 | 1.0008 | 1.0016 | 1.0486 | |
| T47DKBLUC | Unknown | Unknown | SB-3CT | MMP2/9 | MMP | 33.3 | uM | 12608.168 | 0.9827 | 0.9669 | 1.0486 | |
| T47DKBLUC | Unknown | Unknown | SB-3CT | MMP2/9 | MMP | 167 | uM | 12608.168 | 0.9848 | 0.9710 | 1.0486 | |
| UACC-812 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 10580.144 | 1.0017 | 1.0039 | 0.8541 | |
| UACC-812 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 10580.144 | 0.9472 | 0.8769 | 0.8541 | |
| UACC-812 | HER2amp | Luminal | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 10580.144 | 0.9211 | 0.8165 | 0.8541 |