Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM225CWN | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 20 | uM | 12098.144 | 0.9142 | 0.8554 | 1.1959 | |
| SUM225CWN | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 100 | uM | 12098.144 | 0.8304 | 0.7121 | 1.1959 | |
| SUM229PE | TNBC | - | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 11058.144 | 0.9327 | 0.9353 | 2.1171 | |
| SUM229PE | TNBC | - | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 11058.144 | 1.0573 | 1.0534 | 2.1171 | |
| SUM229PE | TNBC | - | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 11058.144 | 0.9568 | 0.9587 | 2.1171 | |
| SUM229PE | TNBC | - | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 11058.144 | 1.0472 | 1.0440 | 2.1171 | |
| SUM229PE | TNBC | - | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 11058.144 | 0.9548 | 0.9568 | 2.1171 | |
| SUM229PE | TNBC | - | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 11058.144 | 1.0172 | 1.0162 | 2.1171 | |
| SUM229PE | TNBC | - | SB-3CT | MMP2/9 | MMP | 4 | uM | 11058.144 | 1.0556 | 1.0518 | 2.1171 | |
| SUM229PE | TNBC | - | SB-3CT | MMP2/9 | MMP | 20 | uM | 11058.144 | 0.9316 | 0.9341 | 2.1171 | |
| SUM229PE | TNBC | - | SB-3CT | MMP2/9 | MMP | 100 | uM | 11058.144 | 0.7446 | 0.7399 | 2.1171 | |
| SUM52PE | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 10695.144 | 1.0791 | 1.1273 | 1.2333 | |
| SUM52PE | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 10695.144 | 1.0698 | 1.1124 | 1.2333 | |
| SUM52PE | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 10695.144 | 1.1606 | 1.2567 | 1.2333 | |
| SUM52PE | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 10695.144 | 1.0723 | 1.1164 | 1.2333 | |
| SUM52PE | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 10695.144 | 1.0871 | 1.1401 | 1.2333 | |
| SUM52PE | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 10695.144 | 1.0776 | 1.1250 | 1.2333 | |
| SUM52PE | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 4 | uM | 10695.144 | 1.0370 | 1.0598 | 1.2333 | |
| SUM52PE | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 20 | uM | 10695.144 | 0.7468 | 0.5785 | 1.2333 | |
| SUM52PE | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 100 | uM | 10695.144 | 0.0361 | -0.8646 | 1.2333 | |
| SUM52PE | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 11852.144 | 1.0420 | 1.0649 | 1.2876 | |
| SUM52PE | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 11852.144 | 1.0359 | 1.0556 | 1.2876 | |
| SUM52PE | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 11852.144 | 1.0153 | 1.0237 | 1.2876 | |
| SUM52PE | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 11852.144 | 1.0235 | 1.0364 | 1.2876 | |
| SUM52PE | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 11852.144 | 1.0929 | 1.1429 | 1.2876 |