Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM185PE | TNBC | Luminal | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 12269.144 | 1.0121 | 1.0236 | 1.0241 | |
| SUM185PE | TNBC | Luminal | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 12269.144 | 0.9319 | 0.8669 | 1.0241 | |
| SUM185PE | TNBC | Luminal | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 12269.144 | 1.0081 | 1.0158 | 1.0241 | |
| SUM185PE | TNBC | Luminal | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 12269.144 | 0.9628 | 0.9273 | 1.0241 | |
| SUM185PE | TNBC | Luminal | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 12269.144 | 0.6917 | 0.3955 | 1.0241 | |
| SUM185PE | TNBC | Luminal | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 12269.144 | 1.0277 | 1.0540 | 1.0241 | |
| SUM185PE | TNBC | Luminal | SB-3CT | MMP2/9 | MMP | 4 | uM | 12269.144 | 0.9721 | 0.9454 | 1.0241 | |
| SUM185PE | TNBC | Luminal | SB-3CT | MMP2/9 | MMP | 20 | uM | 12269.144 | 0.6375 | 0.2885 | 1.0241 | |
| SUM185PE | TNBC | Luminal | SB-3CT | MMP2/9 | MMP | 100 | uM | 12269.144 | 0.5714 | 0.1579 | 1.0241 | |
| SUM225CWN | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 10579.144 | 1.1203 | 1.2519 | 0.9576 | |
| SUM225CWN | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 10579.144 | 1.0765 | 1.1601 | 0.9576 | |
| SUM225CWN | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 10579.144 | 1.1094 | 1.2289 | 0.9576 | |
| SUM225CWN | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 10579.144 | 1.1412 | 1.2959 | 0.9576 | |
| SUM225CWN | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 10579.144 | 1.0082 | 1.0170 | 0.9576 | |
| SUM225CWN | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 10579.144 | 0.9987 | 0.9973 | 0.9576 | |
| SUM225CWN | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 4 | uM | 10579.144 | 1.0964 | 1.2018 | 0.9576 | |
| SUM225CWN | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 20 | uM | 10579.144 | 0.9327 | 0.8597 | 0.9576 | |
| SUM225CWN | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 100 | uM | 10579.144 | 0.9952 | 0.9900 | 0.9576 | |
| SUM225CWN | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 12098.144 | 1.0191 | 1.0319 | 1.1959 | |
| SUM225CWN | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 12098.144 | 1.0448 | 1.0747 | 1.1959 | |
| SUM225CWN | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 12098.144 | 1.0072 | 1.0120 | 1.1959 | |
| SUM225CWN | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 12098.144 | 1.0671 | 1.1116 | 1.1959 | |
| SUM225CWN | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 12098.144 | 0.9369 | 0.8939 | 1.1959 | |
| SUM225CWN | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 12098.144 | 1.0615 | 1.1023 | 1.1959 | |
| SUM225CWN | HER2amp | Basal A | SB-3CT | MMP2/9 | MMP | 4 | uM | 12098.144 | 1.0268 | 1.0447 | 1.1959 |