Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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MCF 10F | NM | - | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 12254.144 | 1.0041 | 1.0043 | 1.8842 | |
MCF 10F | NM | - | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 12254.144 | 1.0233 | 1.0246 | 1.8842 | |
MCF 10F | NM | - | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 12254.144 | 1.0343 | 1.0361 | 1.8842 | |
MCF 10F | NM | - | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 12254.144 | 0.9811 | 0.9799 | 1.8842 | |
MCF 10F | NM | - | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 12254.144 | 0.9661 | 0.9637 | 1.8842 | |
MCF 10F | NM | - | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 12254.144 | 1.0386 | 1.0406 | 1.8842 | |
MCF 10F | NM | - | SB-3CT | MMP2/9 | MMP | 4 | uM | 12254.144 | 0.9247 | 0.9186 | 1.8842 | |
MCF 10F | NM | - | SB-3CT | MMP2/9 | MMP | 20 | uM | 12254.144 | 0.9002 | 0.8914 | 1.8842 | |
MCF 10F | NM | - | SB-3CT | MMP2/9 | MMP | 100 | uM | 12254.144 | 0.7860 | 0.7601 | 1.8842 | |
MCF12A | NM | Basal B | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 10817.144 | 0.9990 | 0.9986 | 1.4640 | |
MCF12A | NM | Basal B | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 10817.144 | 0.9584 | 0.9428 | 1.4640 | |
MCF12A | NM | Basal B | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 10817.144 | 1.0312 | 1.0423 | 1.4640 | |
MCF12A | NM | Basal B | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 10817.144 | 1.0125 | 1.0171 | 1.4640 | |
MCF12A | NM | Basal B | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 10817.144 | 0.9965 | 0.9952 | 1.4640 | |
MCF12A | NM | Basal B | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 10817.144 | 1.0195 | 1.0265 | 1.4640 | |
MCF12A | NM | Basal B | SB-3CT | MMP2/9 | MMP | 4 | uM | 10817.144 | 1.0024 | 1.0033 | 1.4640 | |
MCF12A | NM | Basal B | SB-3CT | MMP2/9 | MMP | 20 | uM | 10817.144 | 0.9437 | 0.9224 | 1.4640 | |
MCF12A | NM | Basal B | SB-3CT | MMP2/9 | MMP | 100 | uM | 10817.144 | 0.9423 | 0.9205 | 1.4640 | |
MCF12A | NM | Basal B | SB-3CT | MMP2/9 | MMP | 0.000427 | uM | 12365.168 | 0.9804 | 0.9820 | 2.1914 | |
MCF12A | NM | Basal B | SB-3CT | MMP2/9 | MMP | 0.00213 | uM | 12365.168 | 0.8924 | 0.8988 | 2.1914 | |
MCF12A | NM | Basal B | SB-3CT | MMP2/9 | MMP | 0.0107 | uM | 12365.168 | 0.9783 | 0.9800 | 2.1914 | |
MCF12A | NM | Basal B | SB-3CT | MMP2/9 | MMP | 0.0533 | uM | 12365.168 | 0.9484 | 0.9522 | 2.1914 | |
MCF12A | NM | Basal B | SB-3CT | MMP2/9 | MMP | 0.267 | uM | 12365.168 | 0.9638 | 0.9667 | 2.1914 | |
MCF12A | NM | Basal B | SB-3CT | MMP2/9 | MMP | 1.33 | uM | 12365.168 | 0.9779 | 0.9797 | 2.1914 | |
MCF12A | NM | Basal B | SB-3CT | MMP2/9 | MMP | 6.67 | uM | 12365.168 | 0.9631 | 0.9660 | 2.1914 |