Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-483 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 11855.144 | 0.9591 | 0.8648 | 0.5961 | |
| BT-483 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 11855.144 | 0.9669 | 0.8903 | 0.5961 | |
| BT-483 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 11855.144 | 0.9128 | 0.7160 | 0.5961 | |
| BT-483 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 11855.144 | 0.9808 | 0.9359 | 0.5961 | |
| BT-483 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 4 | uM | 11855.144 | 0.9442 | 0.8163 | 0.5961 | |
| BT-483 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 20 | uM | 11855.144 | 0.8816 | 0.6188 | 0.5961 | |
| BT-483 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 100 | uM | 11855.144 | 0.1449 | -0.9217 | 0.5961 | |
| BT-549 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.000427 | uM | 12305.168 | 1.0231 | 1.0184 | 2.5025 | |
| BT-549 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.00213 | uM | 12305.168 | 1.0173 | 1.0138 | 2.5025 | |
| BT-549 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.0107 | uM | 12305.168 | 1.1098 | 1.0850 | 2.5025 | |
| BT-549 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.0533 | uM | 12305.168 | 1.0472 | 1.0372 | 2.5025 | |
| BT-549 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 0.267 | uM | 12305.168 | 0.9603 | 0.9679 | 2.5025 | |
| BT-549 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 1.33 | uM | 12305.168 | 1.0597 | 1.0469 | 2.5025 | |
| BT-549 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 6.67 | uM | 12305.168 | 0.6129 | 0.6447 | 2.5025 | |
| BT-549 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 33.3 | uM | 12305.168 | 0.0251 | -0.5415 | 2.5025 | |
| BT-549 | TNBC | Basal B | SB-3CT | MMP2/9 | MMP | 167 | uM | 12305.168 | 0.0006 | -0.8997 | 2.5025 | |
| CAMA-1 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 12070.144 | 0.9411 | 0.8993 | 1.1742 | |
| CAMA-1 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 12070.144 | 0.9354 | 0.8894 | 1.1742 | |
| CAMA-1 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 12070.144 | 0.9962 | 0.9935 | 1.1742 | |
| CAMA-1 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 12070.144 | 0.9792 | 0.9645 | 1.1742 | |
| CAMA-1 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 12070.144 | 0.9332 | 0.8856 | 1.1742 | |
| CAMA-1 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 12070.144 | 0.9723 | 0.9527 | 1.1742 | |
| CAMA-1 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 4 | uM | 12070.144 | 0.9594 | 0.9307 | 1.1742 | |
| CAMA-1 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 20 | uM | 12070.144 | 0.9464 | 0.9083 | 1.1742 | |
| CAMA-1 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 100 | uM | 12070.144 | 0.9019 | 0.8317 | 1.1742 |