Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LY2 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.0107 | uM | 12319.168 | 1.0477 | 1.1000 | 0.9560 | |
| LY2 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.0533 | uM | 12319.168 | 1.0220 | 1.0461 | 0.9560 | |
| LY2 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 0.267 | uM | 12319.168 | 0.9043 | 0.8002 | 0.9560 | |
| LY2 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 1.33 | uM | 12319.168 | 1.1173 | 1.2460 | 0.9560 | |
| LY2 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 6.67 | uM | 12319.168 | 0.7175 | 0.4132 | 0.9560 | |
| LY2 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 33.3 | uM | 12319.168 | 0.0715 | -0.8733 | 0.9560 | |
| LY2 | HR+ | Luminal | SB-3CT | MMP2/9 | MMP | 167 | uM | 12319.168 | 0.0080 | -0.9871 | 0.9560 | |
| MB 157 | Unknown | Unknown | SB-3CT | MMP2/9 | MMP | 0.000427 | uM | 12580.168 | 0.9488 | 0.9505 | 2.0973 | |
| MB 157 | Unknown | Unknown | SB-3CT | MMP2/9 | MMP | 0.00213 | uM | 12580.168 | 0.9763 | 0.9773 | 2.0973 | |
| MB 157 | Unknown | Unknown | SB-3CT | MMP2/9 | MMP | 0.0107 | uM | 12580.168 | 0.9709 | 0.9720 | 2.0973 | |
| MB 157 | Unknown | Unknown | SB-3CT | MMP2/9 | MMP | 0.0533 | uM | 12580.168 | 0.9588 | 0.9602 | 2.0973 | |
| MB 157 | Unknown | Unknown | SB-3CT | MMP2/9 | MMP | 0.267 | uM | 12580.168 | 0.9234 | 0.9254 | 2.0973 | |
| MB 157 | Unknown | Unknown | SB-3CT | MMP2/9 | MMP | 1.33 | uM | 12580.168 | 0.9702 | 0.9714 | 2.0973 | |
| MB 157 | Unknown | Unknown | SB-3CT | MMP2/9 | MMP | 6.67 | uM | 12580.168 | 0.9013 | 0.9033 | 2.0973 | |
| MB 157 | Unknown | Unknown | SB-3CT | MMP2/9 | MMP | 33.3 | uM | 12580.168 | 0.9206 | 0.9227 | 2.0973 | |
| MB 157 | Unknown | Unknown | SB-3CT | MMP2/9 | MMP | 167 | uM | 12580.168 | 0.8996 | 0.9016 | 2.0973 | |
| MCF 10A | NM | Basal B | SB-3CT | MMP2/9 | MMP | 0.000256 | uM | 11056.144 | 0.9444 | 0.9601 | 2.8424 | |
| MCF 10A | NM | Basal B | SB-3CT | MMP2/9 | MMP | 0.00128 | uM | 11056.144 | 0.9624 | 0.9732 | 2.8424 | |
| MCF 10A | NM | Basal B | SB-3CT | MMP2/9 | MMP | 0.0064 | uM | 11056.144 | 1.0195 | 1.0137 | 2.8424 | |
| MCF 10A | NM | Basal B | SB-3CT | MMP2/9 | MMP | 0.032 | uM | 11056.144 | 1.0664 | 1.0458 | 2.8424 | |
| MCF 10A | NM | Basal B | SB-3CT | MMP2/9 | MMP | 0.16 | uM | 11056.144 | 0.9633 | 0.9738 | 2.8424 | |
| MCF 10A | NM | Basal B | SB-3CT | MMP2/9 | MMP | 0.8 | uM | 11056.144 | 0.9680 | 0.9772 | 2.8424 | |
| MCF 10A | NM | Basal B | SB-3CT | MMP2/9 | MMP | 4 | uM | 11056.144 | 0.9096 | 0.9344 | 2.8424 | |
| MCF 10A | NM | Basal B | SB-3CT | MMP2/9 | MMP | 20 | uM | 11056.144 | 0.7635 | 0.8189 | 2.8424 | |
| MCF 10A | NM | Basal B | SB-3CT | MMP2/9 | MMP | 100 | uM | 11056.144 | 0.5594 | 0.6303 | 2.8424 |