Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | TNBC | Basal A | QNZ | NFkB | NFKB | 0.0107 | uM | 5904.096 | 1.0760 | 1.1564 | 0.9724 | |
| BT-20 | TNBC | Basal A | QNZ | NFkB | NFKB | 0.0533 | uM | 5904.096 | 0.9884 | 0.9761 | 0.9724 | |
| BT-20 | TNBC | Basal A | QNZ | NFkB | NFKB | 0.267 | uM | 5904.096 | 0.8723 | 0.7379 | 0.9724 | |
| BT-20 | TNBC | Basal A | QNZ | NFkB | NFKB | 1.33 | uM | 5904.096 | 0.8010 | 0.5919 | 0.9724 | |
| BT-20 | TNBC | Basal A | QNZ | NFkB | NFKB | 6.67 | uM | 5904.096 | 0.7584 | 0.5049 | 0.9724 | |
| BT-20 | TNBC | Basal A | QNZ | NFkB | NFKB | 33.3 | uM | 5904.096 | 0.7815 | 0.5521 | 0.9724 | |
| BT-474 | HER2amp | Luminal | QNZ | NFkB | NFKB | 0.0000853 | uM | 5905.096 | 1.0447 | 1.0985 | 0.9091 | |
| BT-474 | HER2amp | Luminal | QNZ | NFkB | NFKB | 0.000427 | uM | 5905.096 | 1.0411 | 1.0906 | 0.9091 | |
| BT-474 | HER2amp | Luminal | QNZ | NFkB | NFKB | 0.00213 | uM | 5905.096 | 1.0240 | 1.0528 | 0.9091 | |
| BT-474 | HER2amp | Luminal | QNZ | NFkB | NFKB | 0.0107 | uM | 5905.096 | 0.9704 | 0.9351 | 0.9091 | |
| BT-474 | HER2amp | Luminal | QNZ | NFkB | NFKB | 0.0533 | uM | 5905.096 | 0.5549 | 0.0462 | 0.9091 | |
| BT-474 | HER2amp | Luminal | QNZ | NFkB | NFKB | 0.267 | uM | 5905.096 | 0.4071 | -0.2557 | 0.9091 | |
| BT-474 | HER2amp | Luminal | QNZ | NFkB | NFKB | 1.33 | uM | 5905.096 | 0.4309 | -0.2079 | 0.9091 | |
| BT-474 | HER2amp | Luminal | QNZ | NFkB | NFKB | 6.67 | uM | 5905.096 | 0.4139 | -0.2421 | 0.9091 | |
| BT-474 | HER2amp | Luminal | QNZ | NFkB | NFKB | 33.3 | uM | 5905.096 | 0.2860 | -0.4953 | 0.9091 | |
| BT-549 | TNBC | Basal B | QNZ | NFkB | NFKB | 0.0000853 | uM | 5909.096 | 1.0079 | 1.0052 | 3.0117 | |
| BT-549 | TNBC | Basal B | QNZ | NFkB | NFKB | 0.000427 | uM | 5909.096 | 1.0414 | 1.0271 | 3.0117 | |
| BT-549 | TNBC | Basal B | QNZ | NFkB | NFKB | 0.00213 | uM | 5909.096 | 0.8851 | 0.9206 | 3.0117 | |
| BT-549 | TNBC | Basal B | QNZ | NFkB | NFKB | 0.0107 | uM | 5909.096 | 0.8936 | 0.9267 | 3.0117 | |
| BT-549 | TNBC | Basal B | QNZ | NFkB | NFKB | 0.0533 | uM | 5909.096 | 0.8286 | 0.8790 | 3.0117 | |
| BT-549 | TNBC | Basal B | QNZ | NFkB | NFKB | 0.267 | uM | 5909.096 | 0.6680 | 0.7492 | 3.0117 | |
| BT-549 | TNBC | Basal B | QNZ | NFkB | NFKB | 1.33 | uM | 5909.096 | 0.8151 | 0.8687 | 3.0117 | |
| BT-549 | TNBC | Basal B | QNZ | NFkB | NFKB | 6.67 | uM | 5909.096 | 0.7206 | 0.7939 | 3.0117 | |
| BT-549 | TNBC | Basal B | QNZ | NFkB | NFKB | 33.3 | uM | 5909.096 | 0.7513 | 0.8188 | 3.0117 | |
| HCC1143 | TNBC | Basal A | QNZ | NFkB | NFKB | 0.0000853 | uM | 7430.096 | 0.9599 | 0.9599 | 2.0162 |