Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184B5 | NM | Basal | QNZ | NFkB | NFKB | 0.267 | uM | 5897.096 | 0.0093 | -0.9480 | 1.2810 | |
| 184B5 | NM | Basal | QNZ | NFkB | NFKB | 1.33 | uM | 5897.096 | 0.0113 | -0.9397 | 1.2810 | |
| 184B5 | NM | Basal | QNZ | NFkB | NFKB | 6.67 | uM | 5897.096 | 0.0202 | -0.9049 | 1.2810 | |
| 184B5 | NM | Basal | QNZ | NFkB | NFKB | 33.3 | uM | 5897.096 | 0.0106 | -0.9427 | 1.2810 | |
| 600MPE | HR+ | Luminal | QNZ | NFkB | NFKB | 0.0000853 | uM | 5898.096 | 1.0333 | 1.1000 | 0.6718 | |
| 600MPE | HR+ | Luminal | QNZ | NFkB | NFKB | 0.000427 | uM | 5898.096 | 0.9732 | 0.9207 | 0.6718 | |
| 600MPE | HR+ | Luminal | QNZ | NFkB | NFKB | 0.00213 | uM | 5898.096 | 1.0266 | 1.0797 | 0.6718 | |
| 600MPE | HR+ | Luminal | QNZ | NFkB | NFKB | 0.0107 | uM | 5898.096 | 1.0161 | 1.0481 | 0.6718 | |
| 600MPE | HR+ | Luminal | QNZ | NFkB | NFKB | 0.0533 | uM | 5898.096 | 0.9700 | 0.9113 | 0.6718 | |
| 600MPE | HR+ | Luminal | QNZ | NFkB | NFKB | 0.267 | uM | 5898.096 | 0.8884 | 0.6769 | 0.6718 | |
| 600MPE | HR+ | Luminal | QNZ | NFkB | NFKB | 1.33 | uM | 5898.096 | 0.8589 | 0.5948 | 0.6718 | |
| 600MPE | HR+ | Luminal | QNZ | NFkB | NFKB | 6.67 | uM | 5898.096 | 0.8924 | 0.6881 | 0.6718 | |
| 600MPE | HR+ | Luminal | QNZ | NFkB | NFKB | 33.3 | uM | 5898.096 | 0.9054 | 0.7251 | 0.6718 | |
| AU565 | HER2amp | Luminal | QNZ | NFkB | NFKB | 0.0000853 | uM | 5900.096 | 1.0312 | 1.0222 | 2.7795 | |
| AU565 | HER2amp | Luminal | QNZ | NFkB | NFKB | 0.000427 | uM | 5900.096 | 0.9626 | 0.9728 | 2.7795 | |
| AU565 | HER2amp | Luminal | QNZ | NFkB | NFKB | 0.00213 | uM | 5900.096 | 0.8972 | 0.9234 | 2.7795 | |
| AU565 | HER2amp | Luminal | QNZ | NFkB | NFKB | 0.0107 | uM | 5900.096 | 0.9101 | 0.9333 | 2.7795 | |
| AU565 | HER2amp | Luminal | QNZ | NFkB | NFKB | 0.0533 | uM | 5900.096 | 0.7889 | 0.8365 | 2.7795 | |
| AU565 | HER2amp | Luminal | QNZ | NFkB | NFKB | 0.267 | uM | 5900.096 | 0.6541 | 0.7167 | 2.7795 | |
| AU565 | HER2amp | Luminal | QNZ | NFkB | NFKB | 1.33 | uM | 5900.096 | 0.6889 | 0.7491 | 2.7795 | |
| AU565 | HER2amp | Luminal | QNZ | NFkB | NFKB | 6.67 | uM | 5900.096 | 0.6063 | 0.6705 | 2.7795 | |
| AU565 | HER2amp | Luminal | QNZ | NFkB | NFKB | 33.3 | uM | 5900.096 | 0.5388 | 0.6010 | 2.7795 | |
| BT-20 | TNBC | Basal A | QNZ | NFkB | NFKB | 0.0000853 | uM | 5904.096 | 1.0744 | 1.1533 | 0.9724 | |
| BT-20 | TNBC | Basal A | QNZ | NFkB | NFKB | 0.000427 | uM | 5904.096 | 0.9786 | 0.9560 | 0.9724 | |
| BT-20 | TNBC | Basal A | QNZ | NFkB | NFKB | 0.00213 | uM | 5904.096 | 1.0743 | 1.1530 | 0.9724 |