Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MB 157	Unknown	Unknown	Purvalanol A	CDK1	CDK	167	uM	7482.067	0.3426	0.1498	1.9350
MCF 10A	NM	Basal B	Purvalanol A	CDK1	CDK	0.000427	uM	7483.067	0.9388	0.9620	3.2893
MCF 10A	NM	Basal B	Purvalanol A	CDK1	CDK	0.00213	uM	7483.067	0.9762	0.9854	3.2893
MCF 10A	NM	Basal B	Purvalanol A	CDK1	CDK	0.0107	uM	7483.067	1.0573	1.0342	3.2893
MCF 10A	NM	Basal B	Purvalanol A	CDK1	CDK	0.0533	uM	7483.067	0.9709	0.9821	3.2893
MCF 10A	NM	Basal B	Purvalanol A	CDK1	CDK	0.267	uM	7483.067	0.9303	0.9566	3.2893
MCF 10A	NM	Basal B	Purvalanol A	CDK1	CDK	1.33	uM	7483.067	0.9880	0.9927	3.2893
MCF 10A	NM	Basal B	Purvalanol A	CDK1	CDK	6.67	uM	7483.067	0.9597	0.9752	3.2893
MCF 10A	NM	Basal B	Purvalanol A	CDK1	CDK	33.3	uM	7483.067	0.2158	0.2548	3.2893
MCF 10A	NM	Basal B	Purvalanol A	CDK1	CDK	167	uM	7483.067	0.2172	0.2572	3.2893
MCF 10A	NM	Basal B	Purvalanol A	CDK1	CDK	0.000427	uM	7484.067	0.9244	0.9428	2.7060
MCF 10A	NM	Basal B	Purvalanol A	CDK1	CDK	0.00213	uM	7484.067	0.9118	0.9329	2.7060
MCF 10A	NM	Basal B	Purvalanol A	CDK1	CDK	0.0107	uM	7484.067	0.9264	0.9443	2.7060
MCF 10A	NM	Basal B	Purvalanol A	CDK1	CDK	0.0533	uM	7484.067	1.0454	1.0331	2.7060
MCF 10A	NM	Basal B	Purvalanol A	CDK1	CDK	0.267	uM	7484.067	0.8833	0.9104	2.7060
MCF 10A	NM	Basal B	Purvalanol A	CDK1	CDK	1.33	uM	7484.067	1.0166	1.0122	2.7060
MCF 10A	NM	Basal B	Purvalanol A	CDK1	CDK	6.67	uM	7484.067	0.9378	0.9531	2.7060
MCF 10A	NM	Basal B	Purvalanol A	CDK1	CDK	33.3	uM	7484.067	0.7277	0.7784	2.7060
MCF 10A	NM	Basal B	Purvalanol A	CDK1	CDK	167	uM	7484.067	0.4194	0.4507	2.7060
MCF 10A	NM	Basal B	Purvalanol A	CDK1	CDK	0.000427	uM	7485.067	0.9720	0.9850	3.7597
MCF 10A	NM	Basal B	Purvalanol A	CDK1	CDK	0.00213	uM	7485.067	0.9466	0.9710	3.7597
MCF 10A	NM	Basal B	Purvalanol A	CDK1	CDK	0.0107	uM	7485.067	0.8853	0.9363	3.7597
MCF 10A	NM	Basal B	Purvalanol A	CDK1	CDK	0.0533	uM	7485.067	0.9116	0.9514	3.7597
MCF 10A	NM	Basal B	Purvalanol A	CDK1	CDK	0.267	uM	7485.067	0.9035	0.9467	3.7597
MCF 10A	NM	Basal B	Purvalanol A	CDK1	CDK	1.33	uM	7485.067	0.8826	0.9346	3.7597

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)