Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
AU565	HER2amp	Luminal	Sigma A6730	AKT	AKT	2.67	uM	10880.153	0.5797	0.4483	1.6896
AU565	HER2amp	Luminal	Sigma A6730	AKT	AKT	13.3	uM	10880.153	0.2724	-0.0736	1.6896
AU565	HER2amp	Luminal	Sigma A6730	AKT	AKT	66.7	uM	10880.153	0.0126	-0.8497	1.6896
BT-20	TNBC	Basal A	Sigma A6730	AKT	AKT	0.000171	uM	10581.141	0.9935	0.9795	0.6310
BT-20	TNBC	Basal A	Sigma A6730	AKT	AKT	0.000853	uM	10581.141	0.9547	0.8582	0.6310
BT-20	TNBC	Basal A	Sigma A6730	AKT	AKT	0.00427	uM	10581.141	0.9827	0.9453	0.6310
BT-20	TNBC	Basal A	Sigma A6730	AKT	AKT	0.0213	uM	10581.141	1.0091	1.0291	0.6310
BT-20	TNBC	Basal A	Sigma A6730	AKT	AKT	0.107	uM	10581.141	0.9990	0.9968	0.6310
BT-20	TNBC	Basal A	Sigma A6730	AKT	AKT	0.533	uM	10581.141	0.9700	0.9056	0.6310
BT-20	TNBC	Basal A	Sigma A6730	AKT	AKT	2.67	uM	10581.141	0.9117	0.7273	0.6310
BT-20	TNBC	Basal A	Sigma A6730	AKT	AKT	13.3	uM	10581.141	0.6337	-0.0294	0.6310
BT-20	TNBC	Basal A	Sigma A6730	AKT	AKT	66.7	uM	10581.141	0.0050	-0.9996	0.6310
BT-20	TNBC	Basal A	Sigma A6730	AKT	AKT	0.000171	uM	11854.158	0.9863	0.9801	1.3776
BT-20	TNBC	Basal A	Sigma A6730	AKT	AKT	0.000853	uM	11854.158	0.9547	0.9339	1.3776
BT-20	TNBC	Basal A	Sigma A6730	AKT	AKT	0.00427	uM	11854.158	0.9862	0.9799	1.3776
BT-20	TNBC	Basal A	Sigma A6730	AKT	AKT	0.0213	uM	11854.158	0.9740	0.9622	1.3776
BT-20	TNBC	Basal A	Sigma A6730	AKT	AKT	0.107	uM	11854.158	0.9705	0.9570	1.3776
BT-20	TNBC	Basal A	Sigma A6730	AKT	AKT	0.533	uM	11854.158	0.8970	0.8482	1.3776
BT-20	TNBC	Basal A	Sigma A6730	AKT	AKT	2.67	uM	11854.158	0.9172	0.8784	1.3776
BT-20	TNBC	Basal A	Sigma A6730	AKT	AKT	13.3	uM	11854.158	0.5952	0.3724	1.3776
BT-20	TNBC	Basal A	Sigma A6730	AKT	AKT	66.7	uM	11854.158	0.0141	-0.9093	1.3776
BT-474	HER2amp	Luminal	Sigma A6730	AKT	AKT	0.000171	uM	12056.158	0.9075	0.8137	0.9929
BT-474	HER2amp	Luminal	Sigma A6730	AKT	AKT	0.000853	uM	12056.158	0.9455	0.8903	0.9929
BT-474	HER2amp	Luminal	Sigma A6730	AKT	AKT	0.00427	uM	12056.158	0.8998	0.7982	0.9929
BT-474	HER2amp	Luminal	Sigma A6730	AKT	AKT	0.0213	uM	12056.158	0.9292	0.8574	0.9929

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)