Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | Purvalanol A | CDK1 | CDK | 0.267 | uM | 7450.067 | 1.0622 | 1.0545 | 2.2419 | |
| HCC1806 | TNBC | Basal A | Purvalanol A | CDK1 | CDK | 1.33 | uM | 7450.067 | 0.9848 | 0.9864 | 2.2419 | |
| HCC1806 | TNBC | Basal A | Purvalanol A | CDK1 | CDK | 6.67 | uM | 7450.067 | 1.0687 | 1.0601 | 2.2419 | |
| HCC1806 | TNBC | Basal A | Purvalanol A | CDK1 | CDK | 33.3 | uM | 7450.067 | 0.5348 | 0.5128 | 2.2419 | |
| HCC1806 | TNBC | Basal A | Purvalanol A | CDK1 | CDK | 167 | uM | 7450.067 | 0.4435 | 0.3917 | 2.2419 | |
| HCC1806 | TNBC | Basal A | Purvalanol A | CDK1 | CDK | 0.000427 | uM | 7451.067 | 0.9838 | 0.9842 | 2.0570 | |
| HCC1806 | TNBC | Basal A | Purvalanol A | CDK1 | CDK | 0.00213 | uM | 7451.067 | 0.9857 | 0.9860 | 2.0570 | |
| HCC1806 | TNBC | Basal A | Purvalanol A | CDK1 | CDK | 0.0107 | uM | 7451.067 | 0.9776 | 0.9781 | 2.0570 | |
| HCC1806 | TNBC | Basal A | Purvalanol A | CDK1 | CDK | 0.0533 | uM | 7451.067 | 0.9635 | 0.9641 | 2.0570 | |
| HCC1806 | TNBC | Basal A | Purvalanol A | CDK1 | CDK | 0.267 | uM | 7451.067 | 0.9926 | 0.9928 | 2.0570 | |
| HCC1806 | TNBC | Basal A | Purvalanol A | CDK1 | CDK | 1.33 | uM | 7451.067 | 0.9660 | 0.9667 | 2.0570 | |
| HCC1806 | TNBC | Basal A | Purvalanol A | CDK1 | CDK | 6.67 | uM | 7451.067 | 1.0046 | 1.0044 | 2.0570 | |
| HCC1806 | TNBC | Basal A | Purvalanol A | CDK1 | CDK | 33.3 | uM | 7451.067 | 0.8622 | 0.8609 | 2.0570 | |
| HCC1806 | TNBC | Basal A | Purvalanol A | CDK1 | CDK | 167 | uM | 7451.067 | 0.9404 | 0.9412 | 2.0570 | |
| HCC1937 | TNBC | Basal A | Purvalanol A | CDK1 | CDK | 0.000427 | uM | 7452.067 | 0.9957 | 0.9950 | 1.7112 | |
| HCC1937 | TNBC | Basal A | Purvalanol A | CDK1 | CDK | 0.00213 | uM | 7452.067 | 1.0064 | 1.0074 | 1.7112 | |
| HCC1937 | TNBC | Basal A | Purvalanol A | CDK1 | CDK | 0.0107 | uM | 7452.067 | 1.0086 | 1.0101 | 1.7112 | |
| HCC1937 | TNBC | Basal A | Purvalanol A | CDK1 | CDK | 0.0533 | uM | 7452.067 | 0.9469 | 0.9372 | 1.7112 | |
| HCC1937 | TNBC | Basal A | Purvalanol A | CDK1 | CDK | 0.267 | uM | 7452.067 | 1.0273 | 1.0317 | 1.7112 | |
| HCC1937 | TNBC | Basal A | Purvalanol A | CDK1 | CDK | 1.33 | uM | 7452.067 | 1.0250 | 1.0291 | 1.7112 | |
| HCC1937 | TNBC | Basal A | Purvalanol A | CDK1 | CDK | 6.67 | uM | 7452.067 | 0.9648 | 0.9586 | 1.7112 | |
| HCC1937 | TNBC | Basal A | Purvalanol A | CDK1 | CDK | 33.3 | uM | 7452.067 | 0.5239 | 0.3707 | 1.7112 | |
| HCC1937 | TNBC | Basal A | Purvalanol A | CDK1 | CDK | 167 | uM | 7452.067 | 0.6275 | 0.5232 | 1.7112 | |
| HCC1937 | TNBC | Basal A | Purvalanol A | CDK1 | CDK | 0.000427 | uM | 7453.067 | 1.0400 | 1.0526 | 1.5080 | |
| HCC1937 | TNBC | Basal A | Purvalanol A | CDK1 | CDK | 0.00213 | uM | 7453.067 | 1.0329 | 1.0434 | 1.5080 |