Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184A1 | NM | Basal | Purvalanol A | CDK1 | CDK | 0.00213 | uM | 5894.067 | 0.9673 | 0.9580 | 1.5647 | |
| 184A1 | NM | Basal | Purvalanol A | CDK1 | CDK | 0.0107 | uM | 5894.067 | 1.0650 | 1.0821 | 1.5647 | |
| 184A1 | NM | Basal | Purvalanol A | CDK1 | CDK | 0.0533 | uM | 5894.067 | 1.0639 | 1.0807 | 1.5647 | |
| 184A1 | NM | Basal | Purvalanol A | CDK1 | CDK | 0.267 | uM | 5894.067 | 0.9795 | 0.9737 | 1.5647 | |
| 184A1 | NM | Basal | Purvalanol A | CDK1 | CDK | 1.33 | uM | 5894.067 | 0.8902 | 0.8567 | 1.5647 | |
| 184A1 | NM | Basal | Purvalanol A | CDK1 | CDK | 6.67 | uM | 5894.067 | 0.6386 | 0.5016 | 1.5647 | |
| 184A1 | NM | Basal | Purvalanol A | CDK1 | CDK | 33.3 | uM | 5894.067 | 0.3960 | 0.1064 | 1.5647 | |
| 184A1 | NM | Basal | Purvalanol A | CDK1 | CDK | 167 | uM | 5894.067 | 0.4612 | 0.2196 | 1.5647 | |
| 184A1 | NM | Basal | Purvalanol A | CDK1 | CDK | 0.000427 | uM | 5895.067 | 1.1070 | 1.1500 | 1.4053 | |
| 184A1 | NM | Basal | Purvalanol A | CDK1 | CDK | 0.00213 | uM | 5895.067 | 1.0359 | 1.0509 | 1.4053 | |
| 184A1 | NM | Basal | Purvalanol A | CDK1 | CDK | 0.0107 | uM | 5895.067 | 1.0693 | 1.0977 | 1.4053 | |
| 184A1 | NM | Basal | Purvalanol A | CDK1 | CDK | 0.0533 | uM | 5895.067 | 0.9973 | 0.9961 | 1.4053 | |
| 184A1 | NM | Basal | Purvalanol A | CDK1 | CDK | 0.267 | uM | 5895.067 | 1.0121 | 1.0172 | 1.4053 | |
| 184A1 | NM | Basal | Purvalanol A | CDK1 | CDK | 1.33 | uM | 5895.067 | 0.9803 | 0.9719 | 1.4053 | |
| 184A1 | NM | Basal | Purvalanol A | CDK1 | CDK | 6.67 | uM | 5895.067 | 1.0230 | 1.0326 | 1.4053 | |
| 184A1 | NM | Basal | Purvalanol A | CDK1 | CDK | 33.3 | uM | 5895.067 | 0.8720 | 0.8143 | 1.4053 | |
| 184A1 | NM | Basal | Purvalanol A | CDK1 | CDK | 167 | uM | 5895.067 | 0.5791 | 0.3558 | 1.4053 | |
| 184B5 | NM | Basal | Purvalanol A | CDK1 | CDK | 0.000427 | uM | 5896.067 | 1.0441 | 1.0602 | 1.4536 | |
| 184B5 | NM | Basal | Purvalanol A | CDK1 | CDK | 0.00213 | uM | 5896.067 | 0.9909 | 0.9875 | 1.4536 | |
| 184B5 | NM | Basal | Purvalanol A | CDK1 | CDK | 0.0107 | uM | 5896.067 | 1.0488 | 1.0667 | 1.4536 | |
| 184B5 | NM | Basal | Purvalanol A | CDK1 | CDK | 0.0533 | uM | 5896.067 | 1.0160 | 1.0219 | 1.4536 | |
| 184B5 | NM | Basal | Purvalanol A | CDK1 | CDK | 0.267 | uM | 5896.067 | 0.9883 | 0.9839 | 1.4536 | |
| 184B5 | NM | Basal | Purvalanol A | CDK1 | CDK | 1.33 | uM | 5896.067 | 0.8852 | 0.8391 | 1.4536 | |
| 184B5 | NM | Basal | Purvalanol A | CDK1 | CDK | 6.67 | uM | 5896.067 | 0.5589 | 0.3403 | 1.4536 | |
| 184B5 | NM | Basal | Purvalanol A | CDK1 | CDK | 33.3 | uM | 5896.067 | 0.6441 | 0.4778 | 1.4536 |