Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ZR-75-1 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.606 | uM | 7552.065 | 0.9959 | 0.9927 | 1.1323 | |
| ZR-75-1 | HR+ | Luminal | PS-1145 | IKK | NFKB | 3.03 | uM | 7552.065 | 0.9798 | 0.9643 | 1.1323 | |
| ZR-75-1 | HR+ | Luminal | PS-1145 | IKK | NFKB | 15.2 | uM | 7552.065 | 0.9496 | 0.9107 | 1.1323 | |
| ZR-75-1 | HR+ | Luminal | PS-1145 | IKK | NFKB | 75.8 | uM | 7552.065 | 0.9708 | 0.9483 | 1.1323 | |
| ZR-75-1 | HR+ | Luminal | PS-1145 | IKK | NFKB | 379 | uM | 7552.065 | 1.0165 | 1.0292 | 1.1323 | |
| ZR-75-1 | HR+ | Luminal | PS-1145 | IKK | NFKB | 1890 | uM | 7552.065 | 0.9733 | 0.9528 | 1.1323 | |
| ZR-75-1 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.00485 | uM | 7553.065 | 1.0959 | 1.1859 | 1.0305 | |
| ZR-75-1 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.0243 | uM | 7553.065 | 1.0060 | 1.0116 | 1.0305 | |
| ZR-75-1 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.121 | uM | 7553.065 | 1.0382 | 1.0742 | 1.0305 | |
| ZR-75-1 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.606 | uM | 7553.065 | 1.0365 | 1.0709 | 1.0305 | |
| ZR-75-1 | HR+ | Luminal | PS-1145 | IKK | NFKB | 3.03 | uM | 7553.065 | 1.0094 | 1.0182 | 1.0305 | |
| ZR-75-1 | HR+ | Luminal | PS-1145 | IKK | NFKB | 15.2 | uM | 7553.065 | 0.9949 | 0.9900 | 1.0305 | |
| ZR-75-1 | HR+ | Luminal | PS-1145 | IKK | NFKB | 75.8 | uM | 7553.065 | 1.0601 | 1.1165 | 1.0305 | |
| ZR-75-1 | HR+ | Luminal | PS-1145 | IKK | NFKB | 379 | uM | 7553.065 | 1.0614 | 1.1191 | 1.0305 | |
| ZR-75-1 | HR+ | Luminal | PS-1145 | IKK | NFKB | 1890 | uM | 7553.065 | 1.0428 | 1.0829 | 1.0305 | |
| ZR75B | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.00485 | uM | 7555.065 | 0.9529 | 0.9458 | 1.7561 | |
| ZR75B | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.0243 | uM | 7555.065 | 0.9959 | 0.9953 | 1.7561 | |
| ZR75B | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.121 | uM | 7555.065 | 0.9816 | 0.9789 | 1.7561 | |
| ZR75B | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.606 | uM | 7555.065 | 1.0026 | 1.0029 | 1.7561 | |
| ZR75B | HR+ | Luminal | PS-1145 | IKK | NFKB | 3.03 | uM | 7555.065 | 0.9615 | 0.9558 | 1.7561 | |
| ZR75B | HR+ | Luminal | PS-1145 | IKK | NFKB | 15.2 | uM | 7555.065 | 0.9709 | 0.9667 | 1.7561 | |
| ZR75B | HR+ | Luminal | PS-1145 | IKK | NFKB | 75.8 | uM | 7555.065 | 0.9701 | 0.9658 | 1.7561 | |
| ZR75B | HR+ | Luminal | PS-1145 | IKK | NFKB | 379 | uM | 7555.065 | 1.0183 | 1.0207 | 1.7561 | |
| ZR75B | HR+ | Luminal | PS-1145 | IKK | NFKB | 1890 | uM | 7555.065 | 1.0307 | 1.0347 | 1.7561 | |
| 184A1 | NM | Basal | Purvalanol A | CDK1 | CDK | 0.000427 | uM | 5894.067 | 1.0318 | 1.0404 | 1.5647 |