Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 379 | uM | 7471.065 | 0.8969 | 0.9065 | 2.2733 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 1890 | uM | 7471.065 | 0.8345 | 0.8470 | 2.2733 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.00485 | uM | 7472.065 | 1.2581 | 1.5262 | 0.9830 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.0243 | uM | 7472.065 | 1.5063 | 2.0339 | 0.9830 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.121 | uM | 7472.065 | 0.9694 | 0.9377 | 0.9830 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.606 | uM | 7472.065 | 2.4113 | 3.8964 | 0.9830 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 3.03 | uM | 7472.065 | 1.0742 | 1.1510 | 0.9830 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 15.2 | uM | 7472.065 | 1.9026 | 2.8476 | 0.9830 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 75.8 | uM | 7472.065 | 1.0844 | 1.1718 | 0.9830 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 379 | uM | 7472.065 | 1.7983 | 2.6331 | 0.9830 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 1890 | uM | 7472.065 | 2.3456 | 3.7607 | 0.9830 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.00485 | uM | 7473.065 | 1.0043 | 1.0031 | 2.7686 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.0243 | uM | 7473.065 | 1.0412 | 1.0294 | 2.7686 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.121 | uM | 7473.065 | 1.0273 | 1.0195 | 2.7686 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.606 | uM | 7473.065 | 1.1031 | 1.0722 | 2.7686 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 3.03 | uM | 7473.065 | 0.9157 | 0.9374 | 2.7686 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 15.2 | uM | 7473.065 | 0.9163 | 0.9378 | 2.7686 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 75.8 | uM | 7473.065 | 0.9347 | 0.9518 | 2.7686 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 379 | uM | 7473.065 | 0.9685 | 0.9770 | 2.7686 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 1890 | uM | 7473.065 | 0.9025 | 0.9272 | 2.7686 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.00485 | uM | 7474.065 | 1.0460 | 1.0305 | 2.9702 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.0243 | uM | 7474.065 | 0.9823 | 0.9880 | 2.9702 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.121 | uM | 7474.065 | 0.9563 | 0.9701 | 2.9702 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.606 | uM | 7474.065 | 0.8483 | 0.8922 | 2.9702 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 3.03 | uM | 7474.065 | 0.9758 | 0.9836 | 2.9702 |