Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.00485 | uM | 10418.065 | 1.0198 | 1.0422 | 0.9401 | |
| HCC38 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.0243 | uM | 10418.065 | 1.0173 | 1.0369 | 0.9401 | |
| HCC38 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.121 | uM | 10418.065 | 0.8455 | 0.6731 | 0.9401 | |
| HCC38 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.606 | uM | 10418.065 | 1.0109 | 1.0232 | 0.9401 | |
| HCC38 | TNBC | Basal B | PS-1145 | IKK | NFKB | 3.03 | uM | 10418.065 | 1.0378 | 1.0804 | 0.9401 | |
| HCC38 | TNBC | Basal B | PS-1145 | IKK | NFKB | 15.2 | uM | 10418.065 | 0.9671 | 0.9300 | 0.9401 | |
| HCC38 | TNBC | Basal B | PS-1145 | IKK | NFKB | 75.8 | uM | 10418.065 | 1.0607 | 1.1294 | 0.9401 | |
| HCC38 | TNBC | Basal B | PS-1145 | IKK | NFKB | 379 | uM | 10418.065 | 1.0072 | 1.0153 | 0.9401 | |
| HCC38 | TNBC | Basal B | PS-1145 | IKK | NFKB | 1890 | uM | 10418.065 | 0.8844 | 0.7550 | 0.9401 | |
| HCC70 | TNBC | Basal A | PS-1145 | IKK | NFKB | 0.00485 | uM | 7470.065 | 1.0298 | 1.0589 | 1.0127 | |
| HCC70 | TNBC | Basal A | PS-1145 | IKK | NFKB | 0.0243 | uM | 7470.065 | 0.9892 | 0.9787 | 1.0127 | |
| HCC70 | TNBC | Basal A | PS-1145 | IKK | NFKB | 0.121 | uM | 7470.065 | 1.0222 | 1.0438 | 1.0127 | |
| HCC70 | TNBC | Basal A | PS-1145 | IKK | NFKB | 0.606 | uM | 7470.065 | 1.0664 | 1.1311 | 1.0127 | |
| HCC70 | TNBC | Basal A | PS-1145 | IKK | NFKB | 3.03 | uM | 7470.065 | 1.0263 | 1.0520 | 1.0127 | |
| HCC70 | TNBC | Basal A | PS-1145 | IKK | NFKB | 15.2 | uM | 7470.065 | 1.0128 | 1.0254 | 1.0127 | |
| HCC70 | TNBC | Basal A | PS-1145 | IKK | NFKB | 75.8 | uM | 7470.065 | 0.9911 | 0.9825 | 1.0127 | |
| HCC70 | TNBC | Basal A | PS-1145 | IKK | NFKB | 379 | uM | 7470.065 | 0.9960 | 0.9920 | 1.0127 | |
| HCC70 | TNBC | Basal A | PS-1145 | IKK | NFKB | 1890 | uM | 7470.065 | 0.9229 | 0.8477 | 1.0127 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.00485 | uM | 7471.065 | 1.0192 | 1.0168 | 2.2733 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.0243 | uM | 7471.065 | 0.9704 | 0.9738 | 2.2733 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.121 | uM | 7471.065 | 0.9617 | 0.9659 | 2.2733 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.606 | uM | 7471.065 | 1.0028 | 1.0024 | 2.2733 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 3.03 | uM | 7471.065 | 1.0259 | 1.0226 | 2.2733 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 15.2 | uM | 7471.065 | 0.9727 | 0.9758 | 2.2733 | |
| Hs 578T | TNBC | Basal B | PS-1145 | IKK | NFKB | 75.8 | uM | 7471.065 | 1.0826 | 1.0711 | 2.2733 |