Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | PS-1145 | IKK | NFKB | 0.121 | uM | 7467.065 | 1.0011 | 1.0018 | 1.2393 | |
| HCC3153 | TNBC | Basal A | PS-1145 | IKK | NFKB | 0.606 | uM | 7467.065 | 1.0895 | 1.1431 | 1.2393 | |
| HCC3153 | TNBC | Basal A | PS-1145 | IKK | NFKB | 3.03 | uM | 7467.065 | 1.0301 | 1.0484 | 1.2393 | |
| HCC3153 | TNBC | Basal A | PS-1145 | IKK | NFKB | 15.2 | uM | 7467.065 | 1.0306 | 1.0492 | 1.2393 | |
| HCC3153 | TNBC | Basal A | PS-1145 | IKK | NFKB | 75.8 | uM | 7467.065 | 1.0203 | 1.0327 | 1.2393 | |
| HCC3153 | TNBC | Basal A | PS-1145 | IKK | NFKB | 379 | uM | 7467.065 | 1.0867 | 1.1388 | 1.2393 | |
| HCC3153 | TNBC | Basal A | PS-1145 | IKK | NFKB | 1890 | uM | 7467.065 | 1.1153 | 1.1841 | 1.2393 | |
| HCC38 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.00485 | uM | 7468.065 | 1.0068 | 1.0090 | 1.5219 | |
| HCC38 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.0243 | uM | 7468.065 | 0.9538 | 0.9387 | 1.5219 | |
| HCC38 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.121 | uM | 7468.065 | 0.9622 | 0.9500 | 1.5219 | |
| HCC38 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.606 | uM | 7468.065 | 0.9523 | 0.9367 | 1.5219 | |
| HCC38 | TNBC | Basal B | PS-1145 | IKK | NFKB | 3.03 | uM | 7468.065 | 0.9892 | 0.9858 | 1.5219 | |
| HCC38 | TNBC | Basal B | PS-1145 | IKK | NFKB | 15.2 | uM | 7468.065 | 0.9010 | 0.8675 | 1.5219 | |
| HCC38 | TNBC | Basal B | PS-1145 | IKK | NFKB | 75.8 | uM | 7468.065 | 0.9671 | 0.9565 | 1.5219 | |
| HCC38 | TNBC | Basal B | PS-1145 | IKK | NFKB | 379 | uM | 7468.065 | 0.8843 | 0.8447 | 1.5219 | |
| HCC38 | TNBC | Basal B | PS-1145 | IKK | NFKB | 1890 | uM | 7468.065 | 0.8911 | 0.8541 | 1.5219 | |
| HCC38 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.00485 | uM | 7469.065 | 1.0524 | 1.0517 | 2.0006 | |
| HCC38 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.0243 | uM | 7469.065 | 1.0452 | 1.0447 | 2.0006 | |
| HCC38 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.121 | uM | 7469.065 | 1.0073 | 1.0073 | 2.0006 | |
| HCC38 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.606 | uM | 7469.065 | 1.0455 | 1.0450 | 2.0006 | |
| HCC38 | TNBC | Basal B | PS-1145 | IKK | NFKB | 3.03 | uM | 7469.065 | 1.0018 | 1.0018 | 2.0006 | |
| HCC38 | TNBC | Basal B | PS-1145 | IKK | NFKB | 15.2 | uM | 7469.065 | 0.9614 | 0.9610 | 2.0006 | |
| HCC38 | TNBC | Basal B | PS-1145 | IKK | NFKB | 75.8 | uM | 7469.065 | 0.9629 | 0.9626 | 2.0006 | |
| HCC38 | TNBC | Basal B | PS-1145 | IKK | NFKB | 379 | uM | 7469.065 | 0.9315 | 0.9303 | 2.0006 | |
| HCC38 | TNBC | Basal B | PS-1145 | IKK | NFKB | 1890 | uM | 7469.065 | 0.9178 | 0.9161 | 2.0006 |