Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMA-1 | HR+ | Luminal | PS-1145 | IKK | NFKB | 3.03 | uM | 5911.065 | 0.9572 | 0.8879 | 0.7592 | |
| CAMA-1 | HR+ | Luminal | PS-1145 | IKK | NFKB | 15.2 | uM | 5911.065 | 0.9712 | 0.9244 | 0.7592 | |
| CAMA-1 | HR+ | Luminal | PS-1145 | IKK | NFKB | 75.8 | uM | 5911.065 | 0.9550 | 0.8822 | 0.7592 | |
| CAMA-1 | HR+ | Luminal | PS-1145 | IKK | NFKB | 379 | uM | 5911.065 | 0.8534 | 0.6231 | 0.7592 | |
| CAMA-1 | HR+ | Luminal | PS-1145 | IKK | NFKB | 1890 | uM | 5911.065 | 0.8330 | 0.5720 | 0.7592 | |
| CAMA-1 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.00485 | uM | 5912.065 | 0.9452 | 0.9045 | 1.1516 | |
| CAMA-1 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.0243 | uM | 5912.065 | 0.9459 | 0.9056 | 1.1516 | |
| CAMA-1 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.121 | uM | 5912.065 | 0.9812 | 0.9673 | 1.1516 | |
| CAMA-1 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.606 | uM | 5912.065 | 1.0010 | 1.0018 | 1.1516 | |
| CAMA-1 | HR+ | Luminal | PS-1145 | IKK | NFKB | 3.03 | uM | 5912.065 | 0.9422 | 0.8992 | 1.1516 | |
| CAMA-1 | HR+ | Luminal | PS-1145 | IKK | NFKB | 15.2 | uM | 5912.065 | 0.9901 | 0.9828 | 1.1516 | |
| CAMA-1 | HR+ | Luminal | PS-1145 | IKK | NFKB | 75.8 | uM | 5912.065 | 0.8862 | 0.8009 | 1.1516 | |
| CAMA-1 | HR+ | Luminal | PS-1145 | IKK | NFKB | 379 | uM | 5912.065 | 0.9355 | 0.8874 | 1.1516 | |
| CAMA-1 | HR+ | Luminal | PS-1145 | IKK | NFKB | 1890 | uM | 5912.065 | 0.8099 | 0.6655 | 1.1516 | |
| HCC1143 | TNBC | Basal A | PS-1145 | IKK | NFKB | 0.00485 | uM | 7430.065 | 1.0289 | 1.0299 | 1.9263 | |
| HCC1143 | TNBC | Basal A | PS-1145 | IKK | NFKB | 0.0243 | uM | 7430.065 | 1.1029 | 1.1043 | 1.9263 | |
| HCC1143 | TNBC | Basal A | PS-1145 | IKK | NFKB | 0.121 | uM | 7430.065 | 1.0069 | 1.0072 | 1.9263 | |
| HCC1143 | TNBC | Basal A | PS-1145 | IKK | NFKB | 0.606 | uM | 7430.065 | 1.0778 | 1.0794 | 1.9263 | |
| HCC1143 | TNBC | Basal A | PS-1145 | IKK | NFKB | 3.03 | uM | 7430.065 | 1.1057 | 1.1071 | 1.9263 | |
| HCC1143 | TNBC | Basal A | PS-1145 | IKK | NFKB | 15.2 | uM | 7430.065 | 0.9981 | 0.9981 | 1.9263 | |
| HCC1143 | TNBC | Basal A | PS-1145 | IKK | NFKB | 75.8 | uM | 7430.065 | 1.0272 | 1.0281 | 1.9263 | |
| HCC1143 | TNBC | Basal A | PS-1145 | IKK | NFKB | 379 | uM | 7430.065 | 0.9449 | 0.9420 | 1.9263 | |
| HCC1143 | TNBC | Basal A | PS-1145 | IKK | NFKB | 1890 | uM | 7430.065 | 1.0229 | 1.0237 | 1.9263 | |
| HCC1187 | TNBC | Basal A | PS-1145 | IKK | NFKB | 0.00485 | uM | 7431.065 | 1.0731 | 1.0987 | 1.4650 | |
| HCC1187 | TNBC | Basal A | PS-1145 | IKK | NFKB | 0.0243 | uM | 7431.065 | 0.9786 | 0.9706 | 1.4650 |