Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-483 | HR+ | Luminal | PS-1145 | IKK | NFKB | 75.8 | uM | 5908.065 | 0.9259 | 0.7214 | 0.5136 | |
| BT-483 | HR+ | Luminal | PS-1145 | IKK | NFKB | 379 | uM | 5908.065 | 0.9843 | 0.9395 | 0.5136 | |
| BT-483 | HR+ | Luminal | PS-1145 | IKK | NFKB | 1890 | uM | 5908.065 | 0.9957 | 0.9832 | 0.5136 | |
| BT-549 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.00485 | uM | 5909.065 | 1.0455 | 1.0321 | 2.7890 | |
| BT-549 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.0243 | uM | 5909.065 | 1.0629 | 1.0442 | 2.7890 | |
| BT-549 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.121 | uM | 5909.065 | 0.9912 | 0.9936 | 2.7890 | |
| BT-549 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.606 | uM | 5909.065 | 1.0585 | 1.0412 | 2.7890 | |
| BT-549 | TNBC | Basal B | PS-1145 | IKK | NFKB | 3.03 | uM | 5909.065 | 1.0463 | 1.0327 | 2.7890 | |
| BT-549 | TNBC | Basal B | PS-1145 | IKK | NFKB | 15.2 | uM | 5909.065 | 1.0502 | 1.0355 | 2.7890 | |
| BT-549 | TNBC | Basal B | PS-1145 | IKK | NFKB | 75.8 | uM | 5909.065 | 0.9240 | 0.9441 | 2.7890 | |
| BT-549 | TNBC | Basal B | PS-1145 | IKK | NFKB | 379 | uM | 5909.065 | 0.8962 | 0.9230 | 2.7890 | |
| BT-549 | TNBC | Basal B | PS-1145 | IKK | NFKB | 1890 | uM | 5909.065 | 0.8684 | 0.9014 | 2.7890 | |
| BT-549 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.00485 | uM | 5910.065 | 0.9922 | 0.9951 | 3.2016 | |
| BT-549 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.0243 | uM | 5910.065 | 1.1046 | 1.0631 | 3.2016 | |
| BT-549 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.121 | uM | 5910.065 | 0.9749 | 0.9842 | 3.2016 | |
| BT-549 | TNBC | Basal B | PS-1145 | IKK | NFKB | 0.606 | uM | 5910.065 | 1.1454 | 1.0866 | 3.2016 | |
| BT-549 | TNBC | Basal B | PS-1145 | IKK | NFKB | 3.03 | uM | 5910.065 | 1.0432 | 1.0266 | 3.2016 | |
| BT-549 | TNBC | Basal B | PS-1145 | IKK | NFKB | 15.2 | uM | 5910.065 | 1.0122 | 1.0076 | 3.2016 | |
| BT-549 | TNBC | Basal B | PS-1145 | IKK | NFKB | 75.8 | uM | 5910.065 | 1.0665 | 1.0407 | 3.2016 | |
| BT-549 | TNBC | Basal B | PS-1145 | IKK | NFKB | 379 | uM | 5910.065 | 0.9522 | 0.9696 | 3.2016 | |
| BT-549 | TNBC | Basal B | PS-1145 | IKK | NFKB | 1890 | uM | 5910.065 | 0.8208 | 0.8804 | 3.2016 | |
| CAMA-1 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.00485 | uM | 5911.065 | 0.9750 | 0.9344 | 0.7592 | |
| CAMA-1 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.0243 | uM | 5911.065 | 0.9479 | 0.8639 | 0.7592 | |
| CAMA-1 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.121 | uM | 5911.065 | 0.9687 | 0.9179 | 0.7592 | |
| CAMA-1 | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.606 | uM | 5911.065 | 0.9473 | 0.8623 | 0.7592 |