Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.0374 | uM | 7541.095 | 1.0314 | 1.0430 | 1.4542 | |
| SUM52PE | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.187 | uM | 7541.095 | 0.9988 | 0.9983 | 1.4542 | |
| SUM52PE | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.936 | uM | 7541.095 | 1.0494 | 1.0674 | 1.4542 | |
| SUM52PE | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 4.68 | uM | 7541.095 | 1.0231 | 1.0317 | 1.4542 | |
| SUM52PE | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 23.4 | uM | 7541.095 | 0.9536 | 0.9357 | 1.4542 | |
| SUM52PE | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 117 | uM | 7541.095 | 0.8770 | 0.8273 | 1.4542 | |
| SUM52PE | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 585 | uM | 7541.095 | 0.9389 | 0.9151 | 1.4542 | |
| SUM52PE | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 2920 | uM | 7541.095 | 0.8594 | 0.8021 | 1.4542 | |
| T47D | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.00749 | uM | 7542.095 | 0.9767 | 0.9638 | 1.2904 | |
| T47D | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.0374 | uM | 7542.095 | 1.0017 | 1.0026 | 1.2904 | |
| T47D | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.187 | uM | 7542.095 | 0.9561 | 0.9316 | 1.2904 | |
| T47D | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.936 | uM | 7542.095 | 0.9494 | 0.9211 | 1.2904 | |
| T47D | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 4.68 | uM | 7542.095 | 0.9714 | 0.9556 | 1.2904 | |
| T47D | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 23.4 | uM | 7542.095 | 0.9572 | 0.9334 | 1.2904 | |
| T47D | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 117 | uM | 7542.095 | 0.9601 | 0.9379 | 1.2904 | |
| T47D | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 585 | uM | 7542.095 | 0.9278 | 0.8872 | 1.2904 | |
| T47D | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 2920 | uM | 7542.095 | 0.9834 | 0.9742 | 1.2904 | |
| T47D | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.00749 | uM | 7543.095 | 1.0489 | 1.0821 | 1.1854 | |
| T47D | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.0374 | uM | 7543.095 | 1.0431 | 1.0724 | 1.1854 | |
| T47D | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.187 | uM | 7543.095 | 1.0451 | 1.0759 | 1.1854 | |
| T47D | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.936 | uM | 7543.095 | 0.9558 | 0.9252 | 1.1854 | |
| T47D | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 4.68 | uM | 7543.095 | 0.9276 | 0.8771 | 1.1854 | |
| T47D | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 23.4 | uM | 7543.095 | 0.9383 | 0.8953 | 1.1854 | |
| T47D | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 117 | uM | 7543.095 | 0.9212 | 0.8661 | 1.1854 | |
| T47D | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 585 | uM | 7543.095 | 0.9565 | 0.9263 | 1.1854 |