Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-134-VI | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 23.4 | uM | 7494.094 | 0.8947 | 0.7853 | 0.9794 | |
| MDA-MB-134-VI | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 117 | uM | 7494.094 | 0.9414 | 0.8803 | 0.9794 | |
| MDA-MB-134-VI | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 585 | uM | 7494.094 | 0.9215 | 0.8398 | 0.9794 | |
| MDA-MB-134-VI | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 2920 | uM | 7494.094 | 0.9121 | 0.8207 | 0.9794 | |
| MDA-MB-134-VI | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.00749 | uM | 10419.095 | 0.9234 | 0.7985 | 0.7505 | |
| MDA-MB-134-VI | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.0374 | uM | 10419.095 | 0.9337 | 0.8253 | 0.7505 | |
| MDA-MB-134-VI | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.187 | uM | 10419.095 | 0.9228 | 0.7970 | 0.7505 | |
| MDA-MB-134-VI | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.936 | uM | 10419.095 | 0.9216 | 0.7939 | 0.7505 | |
| MDA-MB-134-VI | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 4.68 | uM | 10419.095 | 0.9180 | 0.7845 | 0.7505 | |
| MDA-MB-134-VI | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 23.4 | uM | 10419.095 | 0.8780 | 0.6816 | 0.7505 | |
| MDA-MB-134-VI | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 117 | uM | 10419.095 | 0.8735 | 0.6701 | 0.7505 | |
| MDA-MB-134-VI | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 585 | uM | 10419.095 | 0.8735 | 0.6703 | 0.7505 | |
| MDA-MB-134-VI | HR+ | Luminal | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 2920 | uM | 10419.095 | 0.9060 | 0.7534 | 0.7505 | |
| MDA-MB-157 | TNBC | Basal B | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.00749 | uM | 7496.095 | 0.5927 | 0.2065 | 1.0348 | |
| MDA-MB-157 | TNBC | Basal B | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.0374 | uM | 7496.095 | 0.7884 | 0.5895 | 1.0348 | |
| MDA-MB-157 | TNBC | Basal B | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.187 | uM | 7496.095 | 0.7974 | 0.6071 | 1.0348 | |
| MDA-MB-157 | TNBC | Basal B | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.936 | uM | 7496.095 | 0.6845 | 0.3865 | 1.0348 | |
| MDA-MB-157 | TNBC | Basal B | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 4.68 | uM | 7496.095 | 0.6319 | 0.2835 | 1.0348 | |
| MDA-MB-157 | TNBC | Basal B | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 23.4 | uM | 7496.095 | 0.6642 | 0.3469 | 1.0348 | |
| MDA-MB-157 | TNBC | Basal B | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 117 | uM | 7496.095 | 0.6471 | 0.3134 | 1.0348 | |
| MDA-MB-157 | TNBC | Basal B | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 585 | uM | 7496.095 | 0.6649 | 0.3482 | 1.0348 | |
| MDA-MB-157 | TNBC | Basal B | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 2920 | uM | 7496.095 | 0.8531 | 0.7154 | 1.0348 | |
| MDA-MB-157 | TNBC | Basal B | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.00749 | uM | 7498.095 | 0.9695 | 0.9504 | 1.2329 | |
| MDA-MB-157 | TNBC | Basal B | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.0374 | uM | 7498.095 | 0.9396 | 0.9015 | 1.2329 | |
| MDA-MB-157 | TNBC | Basal B | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.187 | uM | 7498.095 | 0.9183 | 0.8664 | 1.2329 |