Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MB 157 | Unknown | Unknown | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.187 | uM | 7482.095 | 0.7489 | 0.7548 | 2.2108 | |
| MB 157 | Unknown | Unknown | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.936 | uM | 7482.095 | 0.4106 | 0.3372 | 2.2108 | |
| MB 157 | Unknown | Unknown | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 4.68 | uM | 7482.095 | 0.3603 | 0.2604 | 2.2108 | |
| MB 157 | Unknown | Unknown | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 23.4 | uM | 7482.095 | 0.3673 | 0.2714 | 2.2108 | |
| MB 157 | Unknown | Unknown | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 117 | uM | 7482.095 | 0.3601 | 0.2601 | 2.2108 | |
| MB 157 | Unknown | Unknown | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 585 | uM | 7482.095 | 0.3864 | 0.3008 | 2.2108 | |
| MB 157 | Unknown | Unknown | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 2920 | uM | 7482.095 | 0.4842 | 0.4407 | 2.2108 | |
| MCF 10A | NM | Basal B | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.00749 | uM | 7483.095 | 1.1954 | 1.1381 | 2.6732 | |
| MCF 10A | NM | Basal B | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.0374 | uM | 7483.095 | 1.2258 | 1.1583 | 2.6732 | |
| MCF 10A | NM | Basal B | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.187 | uM | 7483.095 | 1.1563 | 1.1117 | 2.6732 | |
| MCF 10A | NM | Basal B | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.936 | uM | 7483.095 | 1.1451 | 1.1040 | 2.6732 | |
| MCF 10A | NM | Basal B | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 4.68 | uM | 7483.095 | 1.1338 | 1.0962 | 2.6732 | |
| MCF 10A | NM | Basal B | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 23.4 | uM | 7483.095 | 1.1674 | 1.1192 | 2.6732 | |
| MCF 10A | NM | Basal B | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 117 | uM | 7483.095 | 1.2077 | 1.1463 | 2.6732 | |
| MCF 10A | NM | Basal B | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 585 | uM | 7483.095 | 1.3409 | 1.2320 | 2.6732 | |
| MCF 10A | NM | Basal B | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 2920 | uM | 7483.095 | 1.2696 | 1.1868 | 2.6732 | |
| MCF 10A | NM | Basal B | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.00749 | uM | 7484.094 | 0.9874 | 0.9905 | 2.6561 | |
| MCF 10A | NM | Basal B | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.0374 | uM | 7484.094 | 1.0056 | 1.0042 | 2.6561 | |
| MCF 10A | NM | Basal B | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.187 | uM | 7484.094 | 0.9494 | 0.9613 | 2.6561 | |
| MCF 10A | NM | Basal B | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.936 | uM | 7484.094 | 0.7767 | 0.8185 | 2.6561 | |
| MCF 10A | NM | Basal B | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 4.68 | uM | 7484.094 | 0.6137 | 0.6642 | 2.6561 | |
| MCF 10A | NM | Basal B | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 23.4 | uM | 7484.094 | 0.5260 | 0.5703 | 2.6561 | |
| MCF 10A | NM | Basal B | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 117 | uM | 7484.094 | 0.5067 | 0.5484 | 2.6561 | |
| MCF 10A | NM | Basal B | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 585 | uM | 7484.094 | 0.5939 | 0.6437 | 2.6561 | |
| MCF 10A | NM | Basal B | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 2920 | uM | 7484.094 | 0.7843 | 0.8251 | 2.6561 |