Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.187 | uM | 7451.095 | 0.6613 | 0.6576 | 2.2028 | |
| HCC1806 | TNBC | Basal A | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.936 | uM | 7451.095 | 0.6885 | 0.6882 | 2.2028 | |
| HCC1806 | TNBC | Basal A | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 4.68 | uM | 7451.095 | 0.6997 | 0.7006 | 2.2028 | |
| HCC1806 | TNBC | Basal A | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 23.4 | uM | 7451.095 | 0.6683 | 0.6656 | 2.2028 | |
| HCC1806 | TNBC | Basal A | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 117 | uM | 7451.095 | 0.6620 | 0.6584 | 2.2028 | |
| HCC1806 | TNBC | Basal A | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 585 | uM | 7451.095 | 0.7407 | 0.7452 | 2.2028 | |
| HCC1806 | TNBC | Basal A | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 2920 | uM | 7451.095 | 0.7900 | 0.7970 | 2.2028 | |
| HCC1937 | TNBC | Basal A | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.00749 | uM | 7452.095 | 1.0076 | 1.0088 | 1.7316 | |
| HCC1937 | TNBC | Basal A | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.0374 | uM | 7452.095 | 1.0196 | 1.0225 | 1.7316 | |
| HCC1937 | TNBC | Basal A | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.187 | uM | 7452.095 | 1.0442 | 1.0506 | 1.7316 | |
| HCC1937 | TNBC | Basal A | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.936 | uM | 7452.095 | 1.0904 | 1.1025 | 1.7316 | |
| HCC1937 | TNBC | Basal A | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 4.68 | uM | 7452.095 | 1.1214 | 1.1369 | 1.7316 | |
| HCC1937 | TNBC | Basal A | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 23.4 | uM | 7452.095 | 1.1546 | 1.1731 | 1.7316 | |
| HCC1937 | TNBC | Basal A | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 117 | uM | 7452.095 | 0.9203 | 0.9063 | 1.7316 | |
| HCC1937 | TNBC | Basal A | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 585 | uM | 7452.095 | 0.6042 | 0.4951 | 1.7316 | |
| HCC1937 | TNBC | Basal A | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 2920 | uM | 7452.095 | 1.0929 | 1.1053 | 1.7316 | |
| HCC1937 | TNBC | Basal A | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.00749 | uM | 7453.095 | 0.9758 | 0.9703 | 1.6395 | |
| HCC1937 | TNBC | Basal A | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.0374 | uM | 7453.095 | 0.9903 | 0.9882 | 1.6395 | |
| HCC1937 | TNBC | Basal A | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.187 | uM | 7453.095 | 0.9288 | 0.9119 | 1.6395 | |
| HCC1937 | TNBC | Basal A | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 0.936 | uM | 7453.095 | 0.9895 | 0.9871 | 1.6395 | |
| HCC1937 | TNBC | Basal A | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 4.68 | uM | 7453.095 | 0.9425 | 0.9291 | 1.6395 | |
| HCC1937 | TNBC | Basal A | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 23.4 | uM | 7453.095 | 0.9552 | 0.9448 | 1.6395 | |
| HCC1937 | TNBC | Basal A | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 117 | uM | 7453.095 | 0.6946 | 0.6014 | 1.6395 | |
| HCC1937 | TNBC | Basal A | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 585 | uM | 7453.095 | 0.9667 | 0.9591 | 1.6395 | |
| HCC1937 | TNBC | Basal A | Pemetrexed | TYMS/DHFR/GARFT | TYMS | 2920 | uM | 7453.095 | 0.9805 | 0.9761 | 1.6395 |