Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM185PE | TNBC | Luminal | PD184352 | MEK | MAPK | 0.0107 | uM | 12269.155 | 0.7409 | 0.3727 | 0.7969 | |
| SUM185PE | TNBC | Luminal | PD184352 | MEK | MAPK | 0.0107 | uM | 12269.155 | 0.7409 | 0.3727 | 0.7969 | |
| SUM185PE | TNBC | Luminal | PD184352 | MEK | MAPK | 0.0533 | uM | 12269.155 | 1.1680 | 1.4303 | 0.7969 | |
| SUM185PE | TNBC | Luminal | PD184352 | MEK | MAPK | 0.0533 | uM | 12269.155 | 1.1680 | 1.4303 | 0.7969 | |
| SUM185PE | TNBC | Luminal | PD184352 | MEK | MAPK | 0.267 | uM | 12269.155 | 0.8737 | 0.6883 | 0.7969 | |
| SUM185PE | TNBC | Luminal | PD184352 | MEK | MAPK | 0.267 | uM | 12269.155 | 0.8737 | 0.6883 | 0.7969 | |
| SUM185PE | TNBC | Luminal | PD184352 | MEK | MAPK | 1.33 | uM | 12269.155 | 0.8841 | 0.7135 | 0.7969 | |
| SUM185PE | TNBC | Luminal | PD184352 | MEK | MAPK | 1.33 | uM | 12269.155 | 0.8841 | 0.7135 | 0.7969 | |
| SUM185PE | TNBC | Luminal | PD184352 | MEK | MAPK | 6.67 | uM | 12269.155 | 0.7707 | 0.4424 | 0.7969 | |
| SUM185PE | TNBC | Luminal | PD184352 | MEK | MAPK | 6.67 | uM | 12269.155 | 0.7707 | 0.4424 | 0.7969 | |
| SUM185PE | TNBC | Luminal | PD184352 | MEK | MAPK | 33.3 | uM | 12269.155 | 1.1815 | 1.4656 | 0.7969 | |
| SUM185PE | TNBC | Luminal | PD184352 | MEK | MAPK | 33.3 | uM | 12269.155 | 1.1815 | 1.4656 | 0.7969 | |
| SUM225CWN | HER2amp | Basal A | PD184352 | MEK | MAPK | 0.0000853 | uM | 12098.155 | 0.9179 | 0.8433 | 1.0503 | |
| SUM225CWN | HER2amp | Basal A | PD184352 | MEK | MAPK | 0.0000853 | uM | 12098.155 | 0.9179 | 0.8433 | 1.0503 | |
| SUM225CWN | HER2amp | Basal A | PD184352 | MEK | MAPK | 0.000427 | uM | 12098.155 | 0.9192 | 0.8458 | 1.0503 | |
| SUM225CWN | HER2amp | Basal A | PD184352 | MEK | MAPK | 0.000427 | uM | 12098.155 | 0.9192 | 0.8458 | 1.0503 | |
| SUM225CWN | HER2amp | Basal A | PD184352 | MEK | MAPK | 0.00213 | uM | 12098.155 | 0.9961 | 0.9925 | 1.0503 | |
| SUM225CWN | HER2amp | Basal A | PD184352 | MEK | MAPK | 0.00213 | uM | 12098.155 | 0.9961 | 0.9925 | 1.0503 | |
| SUM225CWN | HER2amp | Basal A | PD184352 | MEK | MAPK | 0.0107 | uM | 12098.155 | 0.9395 | 0.8846 | 1.0503 | |
| SUM225CWN | HER2amp | Basal A | PD184352 | MEK | MAPK | 0.0107 | uM | 12098.155 | 0.9395 | 0.8846 | 1.0503 | |
| SUM225CWN | HER2amp | Basal A | PD184352 | MEK | MAPK | 0.0533 | uM | 12098.155 | 0.9626 | 0.9288 | 1.0503 | |
| SUM225CWN | HER2amp | Basal A | PD184352 | MEK | MAPK | 0.0533 | uM | 12098.155 | 0.9626 | 0.9288 | 1.0503 | |
| SUM225CWN | HER2amp | Basal A | PD184352 | MEK | MAPK | 0.267 | uM | 12098.155 | 0.9280 | 0.8626 | 1.0503 | |
| SUM225CWN | HER2amp | Basal A | PD184352 | MEK | MAPK | 0.267 | uM | 12098.155 | 0.9280 | 0.8626 | 1.0503 | |
| SUM225CWN | HER2amp | Basal A | PD184352 | MEK | MAPK | 1.33 | uM | 12098.155 | 0.9435 | 0.8923 | 1.0503 |