Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 33.3 | uM | 7820.016 | 0.7530 | 0.0595 | 0.4466 | |
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 167 | uM | 7820.016 | 0.5163 | -0.5449 | 0.4466 | |
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.000427 | uM | 7821.016 | 1.0160 | 1.1051 | 0.3100 | |
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.00213 | uM | 7821.016 | 0.9901 | 0.9366 | 0.3100 | |
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.0107 | uM | 7821.016 | 1.0561 | 1.3851 | 0.3100 | |
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.0533 | uM | 7821.016 | 0.9580 | 0.7412 | 0.3100 | |
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 0.267 | uM | 7821.016 | 0.9737 | 0.8351 | 0.3100 | |
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 1.33 | uM | 7821.016 | 0.8564 | 0.2129 | 0.3100 | |
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 6.67 | uM | 7821.016 | 0.5891 | -0.6371 | 0.3100 | |
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 33.3 | uM | 7821.016 | 0.7345 | -0.2609 | 0.3100 | |
| HCC1419 | HER2amp | Luminal | AG1478 | EGFR | ErbB | 167 | uM | 7821.016 | 0.6953 | -0.3806 | 0.3100 | |
| HCC1428 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.000427 | uM | 9294.019 | 1.0504 | 1.1175 | 0.8608 | |
| HCC1428 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.00213 | uM | 9294.019 | 0.9577 | 0.9022 | 0.8608 | |
| HCC1428 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.0107 | uM | 9294.019 | 0.9624 | 0.9128 | 0.8608 | |
| HCC1428 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.0533 | uM | 9294.019 | 0.9937 | 0.9853 | 0.8608 | |
| HCC1428 | HR+ | Luminal | AG1478 | EGFR | ErbB | 0.267 | uM | 9294.019 | 0.9673 | 0.9242 | 0.8608 | |
| HCC1428 | HR+ | Luminal | AG1478 | EGFR | ErbB | 1.33 | uM | 9294.019 | 0.8375 | 0.6275 | 0.8608 | |
| HCC1428 | HR+ | Luminal | AG1478 | EGFR | ErbB | 6.67 | uM | 9294.019 | 0.7399 | 0.4094 | 0.8608 | |
| HCC1428 | HR+ | Luminal | AG1478 | EGFR | ErbB | 33.3 | uM | 9294.019 | 0.9281 | 0.8340 | 0.8608 | |
| HCC1428 | HR+ | Luminal | AG1478 | EGFR | ErbB | 167 | uM | 9294.019 | 0.8886 | 0.7436 | 0.8608 | |
| HCC1569 | HER2amp | Basal A | AG1478 | EGFR | ErbB | 0.000427 | uM | 7824.016 | 0.9088 | 0.8916 | 1.7164 | |
| HCC1569 | HER2amp | Basal A | AG1478 | EGFR | ErbB | 0.00213 | uM | 7824.016 | 0.9544 | 0.9464 | 1.7164 | |
| HCC1569 | HER2amp | Basal A | AG1478 | EGFR | ErbB | 0.0107 | uM | 7824.016 | 0.9474 | 0.9380 | 1.7164 | |
| HCC1569 | HER2amp | Basal A | AG1478 | EGFR | ErbB | 0.0533 | uM | 7824.016 | 0.9276 | 0.9143 | 1.7164 | |
| HCC1569 | HER2amp | Basal A | AG1478 | EGFR | ErbB | 0.267 | uM | 7824.016 | 0.9560 | 0.9483 | 1.7164 |