Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | PD 98059 | MEK | MAPK | 0.000128 | uM | 10996.152 | 0.9369 | 0.8046 | 0.6343 | |
| HCC2185 | TNBC | Luminal | PD 98059 | MEK | MAPK | 0.00064 | uM | 10996.152 | 0.9698 | 0.9058 | 0.6343 | |
| HCC2185 | TNBC | Luminal | PD 98059 | MEK | MAPK | 0.0032 | uM | 10996.152 | 0.9468 | 0.8349 | 0.6343 | |
| HCC2185 | TNBC | Luminal | PD 98059 | MEK | MAPK | 0.016 | uM | 10996.152 | 0.9496 | 0.8434 | 0.6343 | |
| HCC2185 | TNBC | Luminal | PD 98059 | MEK | MAPK | 0.08 | uM | 10996.152 | 0.9795 | 0.9357 | 0.6343 | |
| HCC2185 | TNBC | Luminal | PD 98059 | MEK | MAPK | 0.4 | uM | 10996.152 | 0.9513 | 0.8485 | 0.6343 | |
| HCC2185 | TNBC | Luminal | PD 98059 | MEK | MAPK | 2 | uM | 10996.152 | 0.9743 | 0.9195 | 0.6343 | |
| HCC2185 | TNBC | Luminal | PD 98059 | MEK | MAPK | 10 | uM | 10996.152 | 0.8999 | 0.6936 | 0.6343 | |
| HCC2185 | TNBC | Luminal | PD 98059 | MEK | MAPK | 50 | uM | 10996.152 | 0.7812 | 0.3552 | 0.6343 | |
| HCC2185 | TNBC | Luminal | PD 98059 | MEK | MAPK | 0.000256 | uM | 12192.159 | 0.9029 | 0.7661 | 0.8215 | |
| HCC2185 | TNBC | Luminal | PD 98059 | MEK | MAPK | 0.00128 | uM | 12192.159 | 0.8492 | 0.6392 | 0.8215 | |
| HCC2185 | TNBC | Luminal | PD 98059 | MEK | MAPK | 0.0064 | uM | 12192.159 | 0.8575 | 0.6587 | 0.8215 | |
| HCC2185 | TNBC | Luminal | PD 98059 | MEK | MAPK | 0.032 | uM | 12192.159 | 0.8316 | 0.5979 | 0.8215 | |
| HCC2185 | TNBC | Luminal | PD 98059 | MEK | MAPK | 0.16 | uM | 12192.159 | 0.8394 | 0.6162 | 0.8215 | |
| HCC2185 | TNBC | Luminal | PD 98059 | MEK | MAPK | 0.8 | uM | 12192.159 | 0.8584 | 0.6608 | 0.8215 | |
| HCC2185 | TNBC | Luminal | PD 98059 | MEK | MAPK | 4 | uM | 12192.159 | 0.8611 | 0.6671 | 0.8215 | |
| HCC2185 | TNBC | Luminal | PD 98059 | MEK | MAPK | 20 | uM | 12192.159 | 0.7147 | 0.3289 | 0.8215 | |
| HCC2185 | TNBC | Luminal | PD 98059 | MEK | MAPK | 100 | uM | 12192.159 | 0.6390 | 0.1594 | 0.8215 | |
| HCC3153 | TNBC | Basal A | PD 98059 | MEK | MAPK | 0.000256 | uM | 10577.136 | 0.9757 | 0.9511 | 0.9962 | |
| HCC3153 | TNBC | Basal A | PD 98059 | MEK | MAPK | 0.00128 | uM | 10577.136 | 0.9165 | 0.8325 | 0.9962 | |
| HCC3153 | TNBC | Basal A | PD 98059 | MEK | MAPK | 0.0064 | uM | 10577.136 | 0.9417 | 0.8829 | 0.9962 | |
| HCC3153 | TNBC | Basal A | PD 98059 | MEK | MAPK | 0.032 | uM | 10577.136 | 0.9491 | 0.8979 | 0.9962 | |
| HCC3153 | TNBC | Basal A | PD 98059 | MEK | MAPK | 0.16 | uM | 10577.136 | 0.9357 | 0.8709 | 0.9962 | |
| HCC3153 | TNBC | Basal A | PD 98059 | MEK | MAPK | 0.8 | uM | 10577.136 | 0.9444 | 0.8883 | 0.9962 | |
| HCC3153 | TNBC | Basal A | PD 98059 | MEK | MAPK | 4 | uM | 10577.136 | 0.8894 | 0.7780 | 0.9962 |