Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-134-VI | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 2.67 | uM | 10998.147 | 0.5388 | -0.0277 | 0.8573 | |
| MDA-MB-134-VI | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 13.3 | uM | 10998.147 | 0.2007 | -0.6928 | 0.8573 | |
| MDA-MB-134-VI | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 66.7 | uM | 10998.147 | 0.0094 | -0.9914 | 0.8573 | |
| MDA-MB-134-VI | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.000171 | uM | 12206.147 | 1.0200 | 1.0440 | 0.9103 | |
| MDA-MB-134-VI | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.000853 | uM | 12206.147 | 1.0074 | 1.0162 | 0.9103 | |
| MDA-MB-134-VI | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.00427 | uM | 12206.147 | 1.0317 | 1.0698 | 0.9103 | |
| MDA-MB-134-VI | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.0213 | uM | 12206.147 | 1.0381 | 1.0839 | 0.9103 | |
| MDA-MB-134-VI | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.107 | uM | 12206.147 | 0.9479 | 0.8858 | 0.9103 | |
| MDA-MB-134-VI | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.533 | uM | 12206.147 | 0.8157 | 0.5989 | 0.9103 | |
| MDA-MB-134-VI | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 2.67 | uM | 12206.147 | 0.4627 | -0.1423 | 0.9103 | |
| MDA-MB-134-VI | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 13.3 | uM | 12206.147 | 0.1551 | -0.7419 | 0.9103 | |
| MDA-MB-134-VI | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 66.7 | uM | 12206.147 | 0.0119 | -0.9846 | 0.9103 | |
| MDA-MB-157 | TNBC | Basal B | Oxamflatin | HDAC | HDAC | 0.000171 | uM | 12594.147 | 1.1135 | 1.1564 | 1.4279 | |
| MDA-MB-157 | TNBC | Basal B | Oxamflatin | HDAC | HDAC | 0.000853 | uM | 12594.147 | 0.9880 | 0.9831 | 1.4279 | |
| MDA-MB-157 | TNBC | Basal B | Oxamflatin | HDAC | HDAC | 0.00427 | uM | 12594.147 | 0.9559 | 0.9378 | 1.4279 | |
| MDA-MB-157 | TNBC | Basal B | Oxamflatin | HDAC | HDAC | 0.0213 | uM | 12594.147 | 0.9566 | 0.9388 | 1.4279 | |
| MDA-MB-157 | TNBC | Basal B | Oxamflatin | HDAC | HDAC | 0.107 | uM | 12594.147 | 0.9721 | 0.9607 | 1.4279 | |
| MDA-MB-157 | TNBC | Basal B | Oxamflatin | HDAC | HDAC | 0.533 | uM | 12594.147 | 0.7198 | 0.5886 | 1.4279 | |
| MDA-MB-157 | TNBC | Basal B | Oxamflatin | HDAC | HDAC | 2.67 | uM | 12594.147 | 0.3949 | 0.0434 | 1.4279 | |
| MDA-MB-157 | TNBC | Basal B | Oxamflatin | HDAC | HDAC | 13.3 | uM | 12594.147 | 0.0504 | -0.7531 | 1.4279 | |
| MDA-MB-157 | TNBC | Basal B | Oxamflatin | HDAC | HDAC | 66.7 | uM | 12594.147 | 0.0055 | -0.9475 | 1.4279 | |
| MDA-MB-175-VII | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.000171 | uM | 10642.147 | 1.0007 | 1.0021 | 0.6592 | |
| MDA-MB-175-VII | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.000853 | uM | 10642.147 | 0.9902 | 0.9703 | 0.6592 | |
| MDA-MB-175-VII | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.00427 | uM | 10642.147 | 1.0613 | 1.1887 | 0.6592 | |
| MDA-MB-175-VII | HR+ | Luminal | Oxamflatin | HDAC | HDAC | 0.0213 | uM | 10642.147 | 1.0386 | 1.1184 | 0.6592 |