Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | NM | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7867.016 | 1.0075 | 1.0066 | 2.2657 | ||
| MCF 10A | NM | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7867.016 | 1.0746 | 1.0645 | 2.2657 | ||
| MCF 10A | NM | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7867.016 | 0.9915 | 0.9925 | 2.2657 | ||
| MCF 10A | NM | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7867.016 | 1.1236 | 1.1056 | 2.2657 | ||
| MCF 10A | NM | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7867.016 | 1.2725 | 1.2245 | 2.2657 | ||
| MCF 10A | NM | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7867.016 | 1.1940 | 1.1628 | 2.2657 | ||
| MCF 10A | NM | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7867.016 | 0.2116 | 0.0077 | 2.2657 | ||
| MCF 10A | NM | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7867.016 | 0.0135 | -0.7005 | 2.2657 | ||
| MCF 10A | NM | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7868.016 | 1.0049 | 1.0047 | 2.0998 | ||
| MCF 10A | NM | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7868.016 | 1.0997 | 1.0926 | 2.0998 | ||
| MCF 10A | NM | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7868.016 | 1.0043 | 1.0041 | 2.0998 | ||
| MCF 10A | NM | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7868.016 | 0.9492 | 0.9509 | 2.0998 | ||
| MCF 10A | NM | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7868.016 | 0.9767 | 0.9777 | 2.0998 | ||
| MCF 10A | NM | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7868.016 | 1.0633 | 1.0593 | 2.0998 | ||
| MCF 10A | NM | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7868.016 | 0.9934 | 0.9937 | 2.0998 | ||
| MCF 10A | NM | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7868.016 | 0.6185 | 0.5909 | 2.0998 | ||
| MCF 10A | NM | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7868.016 | 0.0011 | -0.9236 | 2.0998 | ||
| MCF 10A | NM | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7870.016 | 1.0782 | 1.0729 | 2.1045 | ||
| MCF 10A | NM | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7870.016 | 0.9583 | 0.9599 | 2.1045 | ||
| MCF 10A | NM | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7870.016 | 1.0262 | 1.0247 | 2.1045 | ||
| MCF 10A | NM | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7870.016 | 1.0686 | 1.0640 | 2.1045 | ||
| MCF 10A | NM | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7870.016 | 1.1366 | 1.1255 | 2.1045 | ||
| MCF 10A | NM | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7870.016 | 1.2651 | 1.2365 | 2.1045 | ||
| MCF 10A | NM | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7870.016 | 1.1387 | 1.1273 | 2.1045 | ||
| MCF 10A | NM | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7870.016 | 1.1691 | 1.1541 | 2.1045 |