Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1954 | HER2amp | Basal A | Omipalisib | PI3K | PI3K | 0.0000853 | uM | 7455.087 | 0.9390 | 0.9047 | 1.2897 | |
| HCC1954 | HER2amp | Basal A | Omipalisib | PI3K | PI3K | 0.000427 | uM | 7455.087 | 0.8594 | 0.7783 | 1.2897 | |
| HCC1954 | HER2amp | Basal A | Omipalisib | PI3K | PI3K | 0.00213 | uM | 7455.087 | 0.7267 | 0.5615 | 1.2897 | |
| HCC1954 | HER2amp | Basal A | Omipalisib | PI3K | PI3K | 0.0107 | uM | 7455.087 | 0.6693 | 0.4649 | 1.2897 | |
| HCC1954 | HER2amp | Basal A | Omipalisib | PI3K | PI3K | 0.0533 | uM | 7455.087 | 0.1876 | -0.4537 | 1.2897 | |
| HCC1954 | HER2amp | Basal A | Omipalisib | PI3K | PI3K | 0.267 | uM | 7455.087 | 0.1013 | -0.6613 | 1.2897 | |
| HCC1954 | HER2amp | Basal A | Omipalisib | PI3K | PI3K | 1.33 | uM | 7455.087 | 0.0927 | -0.6838 | 1.2897 | |
| HCC1954 | HER2amp | Basal A | Omipalisib | PI3K | PI3K | 6.67 | uM | 7455.087 | 0.0684 | -0.7501 | 1.2897 | |
| HCC1954 | HER2amp | Basal A | Omipalisib | PI3K | PI3K | 33.3 | uM | 7455.087 | 0.0681 | -0.7511 | 1.2897 | |
| HCC1954 | HER2amp | Basal A | Omipalisib | PI3K | PI3K | 0.0000853 | uM | 7456.086 | 1.0232 | 1.0244 | 1.8940 | |
| HCC1954 | HER2amp | Basal A | Omipalisib | PI3K | PI3K | 0.000427 | uM | 7456.086 | 0.9403 | 0.9361 | 1.8940 | |
| HCC1954 | HER2amp | Basal A | Omipalisib | PI3K | PI3K | 0.00213 | uM | 7456.086 | 0.9238 | 0.9180 | 1.8940 | |
| HCC1954 | HER2amp | Basal A | Omipalisib | PI3K | PI3K | 0.0107 | uM | 7456.086 | 0.7732 | 0.7461 | 1.8940 | |
| HCC1954 | HER2amp | Basal A | Omipalisib | PI3K | PI3K | 0.0533 | uM | 7456.086 | 0.1935 | -0.1599 | 1.8940 | |
| HCC1954 | HER2amp | Basal A | Omipalisib | PI3K | PI3K | 0.267 | uM | 7456.086 | 0.1096 | -0.3778 | 1.8940 | |
| HCC1954 | HER2amp | Basal A | Omipalisib | PI3K | PI3K | 1.33 | uM | 7456.086 | 0.0806 | -0.4708 | 1.8940 | |
| HCC1954 | HER2amp | Basal A | Omipalisib | PI3K | PI3K | 6.67 | uM | 7456.086 | 0.0600 | -0.5471 | 1.8940 | |
| HCC1954 | HER2amp | Basal A | Omipalisib | PI3K | PI3K | 33.3 | uM | 7456.086 | 0.0302 | -0.6850 | 1.8940 | |
| HCC1954 | HER2amp | Basal A | Omipalisib | PI3K | PI3K | 0.0000853 | uM | 10469.087 | 0.9592 | 0.9483 | 1.5889 | |
| HCC1954 | HER2amp | Basal A | Omipalisib | PI3K | PI3K | 0.000427 | uM | 10469.087 | 0.8907 | 0.8594 | 1.5889 | |
| HCC1954 | HER2amp | Basal A | Omipalisib | PI3K | PI3K | 0.00213 | uM | 10469.087 | 0.8848 | 0.8517 | 1.5889 | |
| HCC1954 | HER2amp | Basal A | Omipalisib | PI3K | PI3K | 0.0107 | uM | 10469.087 | 0.7826 | 0.7140 | 1.5889 | |
| HCC1954 | HER2amp | Basal A | Omipalisib | PI3K | PI3K | 0.0533 | uM | 10469.087 | 0.1784 | -0.3241 | 1.5889 | |
| HCC1954 | HER2amp | Basal A | Omipalisib | PI3K | PI3K | 0.267 | uM | 10469.087 | 0.0850 | -0.5761 | 1.5889 | |
| HCC1954 | HER2amp | Basal A | Omipalisib | PI3K | PI3K | 1.33 | uM | 10469.087 | 0.0696 | -0.6263 | 1.5889 |