Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-453 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7516.066 | 0.9498 | 0.9156 | 1.1944 | |
| MDA-MB-453 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7516.066 | 0.9826 | 0.9708 | 1.1944 | |
| MDA-MB-453 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 7516.066 | 1.0400 | 1.0667 | 1.1944 | |
| MDA-MB-453 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 7516.066 | 0.9874 | 0.9788 | 1.1944 | |
| MDA-MB-453 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 7516.066 | 0.9606 | 0.9338 | 1.1944 | |
| MDA-MB-453 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 7516.066 | 0.9449 | 0.9074 | 1.1944 | |
| MDA-MB-453 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 7516.066 | 0.6471 | 0.3891 | 1.1944 | |
| MDA-MB-453 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 7517.066 | 1.0182 | 1.0275 | 1.3218 | |
| MDA-MB-453 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 7517.066 | 0.9769 | 0.9650 | 1.3218 | |
| MDA-MB-453 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7517.066 | 0.9712 | 0.9562 | 1.3218 | |
| MDA-MB-453 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7517.066 | 1.0471 | 1.0709 | 1.3218 | |
| MDA-MB-453 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 7517.066 | 1.0519 | 1.0780 | 1.3218 | |
| MDA-MB-453 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 7517.066 | 1.0229 | 1.0346 | 1.3218 | |
| MDA-MB-453 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 7517.066 | 1.0503 | 1.0757 | 1.3218 | |
| MDA-MB-453 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 7517.066 | 0.9626 | 0.9432 | 1.3218 | |
| MDA-MB-453 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 7517.066 | 0.8302 | 0.7373 | 1.3218 | |
| MDA-MB-453 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 7518.066 | 0.9299 | 0.9074 | 1.5326 | |
| MDA-MB-453 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 7518.066 | 0.9923 | 0.9899 | 1.5326 | |
| MDA-MB-453 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 7518.066 | 0.9373 | 0.9173 | 1.5326 | |
| MDA-MB-453 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 7518.066 | 0.9949 | 0.9934 | 1.5326 | |
| MDA-MB-453 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 7518.066 | 0.9537 | 0.9391 | 1.5326 | |
| MDA-MB-453 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 7518.066 | 0.9515 | 0.9361 | 1.5326 | |
| MDA-MB-453 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 7518.066 | 0.9419 | 0.9234 | 1.5326 | |
| MDA-MB-453 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 7518.066 | 0.8697 | 0.8259 | 1.5326 | |
| MDA-MB-453 | TNBC | Luminal | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 7518.066 | 0.6455 | 0.5031 | 1.5326 |