Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 600MPE | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 5899.066 | 0.9331 | 0.8131 | 0.7056 | |
| 600MPE | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 5899.066 | 0.9619 | 0.8928 | 0.7056 | |
| 600MPE | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 5899.066 | 0.9779 | 0.9378 | 0.7056 | |
| 600MPE | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 5899.066 | 0.9782 | 0.9385 | 0.7056 | |
| 600MPE | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 5899.066 | 0.9582 | 0.8826 | 0.7056 | |
| 600MPE | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 5899.066 | 0.9351 | 0.8185 | 0.7056 | |
| 600MPE | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 5899.066 | 0.9630 | 0.8958 | 0.7056 | |
| 600MPE | HR+ | Luminal | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 5899.066 | 0.7366 | 0.2966 | 0.7056 | |
| AU565 | HER2amp | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 5900.066 | 0.9700 | 0.9777 | 2.7232 | |
| AU565 | HER2amp | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 5900.066 | 1.0343 | 1.0250 | 2.7232 | |
| AU565 | HER2amp | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 5900.066 | 0.9827 | 0.9872 | 2.7232 | |
| AU565 | HER2amp | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 5900.066 | 1.0010 | 1.0007 | 2.7232 | |
| AU565 | HER2amp | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 5900.066 | 0.9919 | 0.9940 | 2.7232 | |
| AU565 | HER2amp | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 5900.066 | 0.9767 | 0.9827 | 2.7232 | |
| AU565 | HER2amp | Luminal | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 5900.066 | 1.0340 | 1.0247 | 2.7232 | |
| AU565 | HER2amp | Luminal | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 5900.066 | 0.8873 | 0.9141 | 2.7232 | |
| AU565 | HER2amp | Luminal | Nutlin 3a | MDM2 | MDM2 | 66.7 | uM | 5900.066 | 0.2783 | 0.2504 | 2.7232 | |
| AU565 | HER2amp | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.000171 | uM | 5901.066 | 0.9210 | 0.9171 | 1.9445 | |
| AU565 | HER2amp | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.000853 | uM | 5901.066 | 1.0012 | 1.0012 | 1.9445 | |
| AU565 | HER2amp | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.00427 | uM | 5901.066 | 0.9764 | 0.9756 | 1.9445 | |
| AU565 | HER2amp | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.0213 | uM | 5901.066 | 0.9846 | 0.9841 | 1.9445 | |
| AU565 | HER2amp | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.107 | uM | 5901.066 | 1.0280 | 1.0286 | 1.9445 | |
| AU565 | HER2amp | Luminal | Nutlin 3a | MDM2 | MDM2 | 0.533 | uM | 5901.066 | 0.9881 | 0.9877 | 1.9445 | |
| AU565 | HER2amp | Luminal | Nutlin 3a | MDM2 | MDM2 | 2.67 | uM | 5901.066 | 1.0033 | 1.0034 | 1.9445 | |
| AU565 | HER2amp | Luminal | Nutlin 3a | MDM2 | MDM2 | 13.3 | uM | 5901.066 | 0.7936 | 0.7758 | 1.9445 |