Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | HER2amp | Luminal | NU6102 | CDK1/2 | CDK | 66.7 | uM | 11851.147 | 0.5518 | 0.3081 | 1.4004 | |
| SUM1315MO2 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 10875.147 | 1.0348 | 1.0926 | 0.7554 | |
| SUM1315MO2 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 10875.147 | 1.0422 | 1.1124 | 0.7554 | |
| SUM1315MO2 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 10875.147 | 1.0058 | 1.0153 | 0.7554 | |
| SUM1315MO2 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 10875.147 | 0.9572 | 0.8874 | 0.7554 | |
| SUM1315MO2 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.107 | uM | 10875.147 | 1.0059 | 1.0155 | 0.7554 | |
| SUM1315MO2 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.533 | uM | 10875.147 | 0.9387 | 0.8393 | 0.7554 | |
| SUM1315MO2 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 2.67 | uM | 10875.147 | 0.7209 | 0.2969 | 0.7554 | |
| SUM1315MO2 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 13.3 | uM | 10875.147 | 0.5908 | -0.0036 | 0.7554 | |
| SUM1315MO2 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 66.7 | uM | 10875.147 | 0.0461 | -0.9660 | 0.7554 | |
| SUM1315MO2 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 12428.147 | 0.9864 | 0.9608 | 0.6926 | |
| SUM1315MO2 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 12428.147 | 1.0005 | 1.0014 | 0.6926 | |
| SUM1315MO2 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 12428.147 | 0.9823 | 0.9492 | 0.6926 | |
| SUM1315MO2 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 12428.147 | 1.0058 | 1.0169 | 0.6926 | |
| SUM1315MO2 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.107 | uM | 12428.147 | 1.0467 | 1.1364 | 0.6926 | |
| SUM1315MO2 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.533 | uM | 12428.147 | 0.9746 | 0.9271 | 0.6926 | |
| SUM1315MO2 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 2.67 | uM | 12428.147 | 0.8519 | 0.5868 | 0.6926 | |
| SUM1315MO2 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 13.3 | uM | 12428.147 | 0.6097 | -0.0210 | 0.6926 | |
| SUM1315MO2 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 66.7 | uM | 12428.147 | 0.0769 | -0.9508 | 0.6926 | |
| SUM149PT | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 10819.147 | 0.9329 | 0.9368 | 2.1652 | |
| SUM149PT | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 10819.147 | 0.9327 | 0.9367 | 2.1652 | |
| SUM149PT | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 10819.147 | 0.9507 | 0.9538 | 2.1652 | |
| SUM149PT | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 10819.147 | 0.9545 | 0.9575 | 2.1652 | |
| SUM149PT | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.107 | uM | 10819.147 | 0.9823 | 0.9836 | 2.1652 | |
| SUM149PT | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.533 | uM | 10819.147 | 0.9225 | 0.9269 | 2.1652 |