Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47DKBLUC | Unknown | Unknown | Omipalisib | PI3K | PI3K | 1.33 | uM | 7545.087 | 0.2897 | -0.3304 | 1.1323 | |
| T47DKBLUC | Unknown | Unknown | Omipalisib | PI3K | PI3K | 6.67 | uM | 7545.087 | 0.2791 | -0.3521 | 1.1323 | |
| T47DKBLUC | Unknown | Unknown | Omipalisib | PI3K | PI3K | 33.3 | uM | 7545.087 | 0.1860 | -0.5472 | 1.1323 | |
| UACC-812 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 0.0000853 | uM | 7547.087 | 0.9124 | 0.8222 | 0.9847 | |
| UACC-812 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 0.000427 | uM | 7547.087 | 0.6409 | 0.2729 | 0.9847 | |
| UACC-812 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 0.00213 | uM | 7547.087 | 0.7458 | 0.4848 | 0.9847 | |
| UACC-812 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 0.0107 | uM | 7547.087 | 0.5397 | 0.0691 | 0.9847 | |
| UACC-812 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 0.0533 | uM | 7547.087 | 0.4002 | -0.2108 | 0.9847 | |
| UACC-812 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 0.267 | uM | 7547.087 | 0.2909 | -0.4293 | 0.9847 | |
| UACC-812 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 1.33 | uM | 7547.087 | 0.2639 | -0.4830 | 0.9847 | |
| UACC-812 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 6.67 | uM | 7547.087 | 0.2311 | -0.5482 | 0.9847 | |
| UACC-812 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 33.3 | uM | 7547.087 | 0.2475 | -0.5155 | 0.9847 | |
| UACC-812 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 0.0000853 | uM | 10420.087 | 0.9914 | 0.9704 | 0.5834 | |
| UACC-812 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 0.000427 | uM | 10420.087 | 0.8349 | 0.4678 | 0.5834 | |
| UACC-812 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 0.00213 | uM | 10420.087 | 0.8560 | 0.5320 | 0.5834 | |
| UACC-812 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 0.0107 | uM | 10420.087 | 0.7106 | 0.1134 | 0.5834 | |
| UACC-812 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 0.0533 | uM | 10420.087 | 0.4387 | -0.5128 | 0.5834 | |
| UACC-812 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 0.267 | uM | 10420.087 | 0.3121 | -0.7283 | 0.5834 | |
| UACC-812 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 1.33 | uM | 10420.087 | 0.2768 | -0.7788 | 0.5834 | |
| UACC-812 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 6.67 | uM | 10420.087 | 0.2184 | -0.8526 | 0.5834 | |
| UACC-812 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 33.3 | uM | 10420.087 | 0.2968 | -0.7507 | 0.5834 | |
| UACC-812 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 0.0000853 | uM | 10580.087 | 0.9831 | 0.9593 | 0.8285 | |
| UACC-812 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 0.000427 | uM | 10580.087 | 0.8754 | 0.7032 | 0.8285 | |
| UACC-812 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 0.00213 | uM | 10580.087 | 0.8811 | 0.7165 | 0.8285 | |
| UACC-812 | HER2amp | Luminal | Omipalisib | PI3K | PI3K | 0.0107 | uM | 10580.087 | 0.7018 | 0.3044 | 0.8285 |