Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 10937.147 | 1.0590 | 1.0930 | 1.2614 | |
| HCC3153 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 10937.147 | 0.9846 | 0.9755 | 1.2614 | |
| HCC3153 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 10937.147 | 0.9764 | 0.9626 | 1.2614 | |
| HCC3153 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.107 | uM | 10937.147 | 1.0138 | 1.0218 | 1.2614 | |
| HCC3153 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.533 | uM | 10937.147 | 1.0107 | 1.0170 | 1.2614 | |
| HCC3153 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 2.67 | uM | 10937.147 | 0.9987 | 0.9979 | 1.2614 | |
| HCC3153 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 13.3 | uM | 10937.147 | 0.8260 | 0.7187 | 1.2614 | |
| HCC3153 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 66.7 | uM | 10937.147 | 0.1751 | -0.4976 | 1.2614 | |
| HCC38 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 11850.147 | 0.9204 | 0.9229 | 2.1087 | |
| HCC38 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 11850.147 | 0.9483 | 0.9503 | 2.1087 | |
| HCC38 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 11850.147 | 0.9206 | 0.9231 | 2.1087 | |
| HCC38 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 11850.147 | 0.8995 | 0.9020 | 2.1087 | |
| HCC38 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.107 | uM | 11850.147 | 0.9159 | 0.9184 | 2.1087 | |
| HCC38 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.533 | uM | 11850.147 | 0.8860 | 0.8885 | 2.1087 | |
| HCC38 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 2.67 | uM | 11850.147 | 0.8699 | 0.8721 | 2.1087 | |
| HCC38 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 13.3 | uM | 11850.147 | 0.4807 | 0.4131 | 2.1087 | |
| HCC38 | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 66.7 | uM | 11850.147 | 0.0215 | -0.6760 | 2.1087 | |
| HCC70 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 10873.147 | 0.9253 | 0.8837 | 1.2965 | |
| HCC70 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 10873.147 | 0.9417 | 0.9094 | 1.2965 | |
| HCC70 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 10873.147 | 0.9850 | 0.9768 | 1.2965 | |
| HCC70 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 10873.147 | 0.9743 | 0.9602 | 1.2965 | |
| HCC70 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.107 | uM | 10873.147 | 1.0130 | 1.0200 | 1.2965 | |
| HCC70 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 0.533 | uM | 10873.147 | 0.9415 | 0.9092 | 1.2965 | |
| HCC70 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 2.67 | uM | 10873.147 | 0.8401 | 0.7485 | 1.2965 | |
| HCC70 | TNBC | Basal A | NU6102 | CDK1/2 | CDK | 13.3 | uM | 10873.147 | 0.7682 | 0.6318 | 1.2965 |