Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 2.67 | uM | 10819.147 | 0.8044 | 0.8087 | 2.1652 | |
| SUM149PT | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 13.3 | uM | 10819.147 | 0.6181 | 0.6015 | 2.1652 | |
| SUM149PT | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 66.7 | uM | 10819.147 | 0.0171 | -0.6948 | 2.1652 | |
| SUM149PT | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 11937.147 | 0.9283 | 0.9389 | 2.3986 | |
| SUM149PT | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 11937.147 | 0.9629 | 0.9687 | 2.3986 | |
| SUM149PT | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 11937.147 | 0.9918 | 0.9932 | 2.3986 | |
| SUM149PT | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 11937.147 | 0.9790 | 0.9824 | 2.3986 | |
| SUM149PT | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.107 | uM | 11937.147 | 0.9358 | 0.9455 | 2.3986 | |
| SUM149PT | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.533 | uM | 11937.147 | 0.8732 | 0.8901 | 2.3986 | |
| SUM149PT | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 2.67 | uM | 11937.147 | 0.6214 | 0.6401 | 2.3986 | |
| SUM149PT | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 13.3 | uM | 11937.147 | 0.4154 | 0.3867 | 2.3986 | |
| SUM149PT | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 66.7 | uM | 11937.147 | 0.0028 | -0.8275 | 2.3986 | |
| SUM159PT | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 11057.147 | 0.9014 | 0.9485 | 3.9818 | |
| SUM159PT | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 11057.147 | 0.9161 | 0.9565 | 3.9818 | |
| SUM159PT | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 11057.147 | 0.9532 | 0.9761 | 3.9818 | |
| SUM159PT | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 11057.147 | 0.9691 | 0.9843 | 3.9818 | |
| SUM159PT | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.107 | uM | 11057.147 | 0.9193 | 0.9582 | 3.9818 | |
| SUM159PT | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 0.533 | uM | 11057.147 | 0.9088 | 0.9525 | 3.9818 | |
| SUM159PT | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 2.67 | uM | 11057.147 | 0.9427 | 0.9706 | 3.9818 | |
| SUM159PT | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 13.3 | uM | 11057.147 | 0.4331 | 0.6209 | 3.9818 | |
| SUM159PT | TNBC | Basal B | NU6102 | CDK1/2 | CDK | 66.7 | uM | 11057.147 | 0.0324 | -0.1545 | 3.9818 | |
| SUM185PE | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 0.000171 | uM | 12269.147 | 0.4106 | -0.2965 | 0.8519 | |
| SUM185PE | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 0.000853 | uM | 12269.147 | 0.7168 | 0.3529 | 0.8519 | |
| SUM185PE | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 0.00427 | uM | 12269.147 | 1.0123 | 1.0288 | 0.8519 | |
| SUM185PE | TNBC | Luminal | NU6102 | CDK1/2 | CDK | 0.0213 | uM | 12269.147 | 0.7169 | 0.3532 | 0.8519 |