Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10819.145 | 0.0097 | -0.7578 | 2.1971 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10819.145 | 0.0097 | -0.7578 | 2.1971 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10819.145 | 0.0066 | -0.7962 | 2.1971 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10819.145 | 0.0066 | -0.7962 | 2.1971 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 11937.145 | 1.0159 | 1.0134 | 2.3618 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 11937.145 | 1.0159 | 1.0134 | 2.3618 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 11937.145 | 0.9275 | 0.9372 | 2.3618 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 11937.145 | 0.9275 | 0.9372 | 2.3618 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 11937.145 | 0.9768 | 0.9802 | 2.3618 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 11937.145 | 0.9768 | 0.9802 | 2.3618 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 11937.145 | 1.0250 | 1.0210 | 2.3618 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 11937.145 | 1.0250 | 1.0210 | 2.3618 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 11937.145 | 0.6311 | 0.6459 | 2.3618 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.107 | uM | 11937.145 | 0.6311 | 0.6459 | 2.3618 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 11937.145 | 0.0159 | -0.6541 | 2.3618 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.533 | uM | 11937.145 | 0.0159 | -0.6541 | 2.3618 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 11937.145 | 0.0057 | -0.7754 | 2.3618 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 2.67 | uM | 11937.145 | 0.0057 | -0.7754 | 2.3618 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 11937.145 | 0.0073 | -0.7505 | 2.3618 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 11937.145 | 0.0073 | -0.7505 | 2.3618 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 11937.145 | 0.0043 | -0.8017 | 2.3618 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 11937.145 | 0.0043 | -0.8017 | 2.3618 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14284.189 | 0.9650 | 0.9493 | 1.3873 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14284.189 | 0.9650 | 0.9493 | 1.3873 | |
| SUM149PT | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14284.189 | 1.0009 | 1.0014 | 1.3873 |