Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12333.17 | 0.0187 | -0.9948 | 0.6683 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12333.17 | 0.0187 | -0.9948 | 0.6683 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14272.189 | 1.0003 | 1.0011 | 0.5095 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14272.189 | 1.0003 | 1.0011 | 0.5095 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14272.189 | 0.9968 | 0.9873 | 0.5095 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14272.189 | 0.9968 | 0.9873 | 0.5095 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14272.189 | 0.9982 | 0.9927 | 0.5095 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14272.189 | 0.9982 | 0.9927 | 0.5095 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14272.189 | 0.9955 | 0.9824 | 0.5095 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14272.189 | 0.9955 | 0.9824 | 0.5095 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14272.189 | 1.0025 | 1.0097 | 0.5095 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14272.189 | 1.0025 | 1.0097 | 0.5095 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14272.189 | 0.9855 | 0.9436 | 0.5095 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14272.189 | 0.9855 | 0.9436 | 0.5095 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14272.189 | 0.3956 | -0.6760 | 0.5095 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14272.189 | 0.3956 | -0.6760 | 0.5095 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14272.189 | 0.0965 | -0.9797 | 0.5095 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14272.189 | 0.0965 | -0.9797 | 0.5095 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14272.189 | 0.4157 | -0.6430 | 0.5095 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14272.189 | 0.4157 | -0.6430 | 0.5095 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14643.189 | 0.9686 | 0.9273 | 0.8604 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14643.189 | 0.9686 | 0.9273 | 0.8604 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14643.189 | 0.9529 | 0.8909 | 0.8604 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14643.189 | 0.9529 | 0.8909 | 0.8604 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14643.189 | 1.0074 | 1.0173 | 0.8604 |