Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10938.145 | 0.6049 | 0.2703 | 1.1073 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10938.145 | 0.3881 | -0.1492 | 1.1073 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10938.145 | 0.3881 | -0.1492 | 1.1073 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10938.145 | 0.2258 | -0.4784 | 1.1073 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10938.145 | 0.2258 | -0.4784 | 1.1073 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10938.145 | 0.1190 | -0.7075 | 1.1073 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10938.145 | 0.1190 | -0.7075 | 1.1073 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10938.145 | 0.1593 | -0.6193 | 1.1073 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10938.145 | 0.1593 | -0.6193 | 1.1073 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12333.17 | 0.9203 | 0.7662 | 0.6683 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12333.17 | 0.9203 | 0.7662 | 0.6683 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12333.17 | 0.9392 | 0.8207 | 0.6683 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12333.17 | 0.9392 | 0.8207 | 0.6683 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12333.17 | 0.9630 | 0.8903 | 0.6683 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12333.17 | 0.9630 | 0.8903 | 0.6683 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12333.17 | 0.9755 | 0.9271 | 0.6683 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12333.17 | 0.9755 | 0.9271 | 0.6683 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12333.17 | 0.9185 | 0.7611 | 0.6683 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12333.17 | 0.9185 | 0.7611 | 0.6683 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12333.17 | 0.4808 | -0.3314 | 0.6683 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12333.17 | 0.4808 | -0.3314 | 0.6683 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12333.17 | 0.0879 | -0.9475 | 0.6683 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12333.17 | 0.0879 | -0.9475 | 0.6683 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12333.17 | 0.0302 | -0.9894 | 0.6683 | |
| MDA-MB-415 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12333.17 | 0.0302 | -0.9894 | 0.6683 |