Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10998.145 | 0.2286 | -0.5838 | 0.9403 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10998.145 | 0.0290 | -0.9537 | 0.9403 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10998.145 | 0.0290 | -0.9537 | 0.9403 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10998.145 | 0.0124 | -0.9812 | 0.9403 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10998.145 | 0.0124 | -0.9812 | 0.9403 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10998.145 | 0.0097 | -0.9855 | 0.9403 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10998.145 | 0.0097 | -0.9855 | 0.9403 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12206.145 | 0.9853 | 0.9662 | 0.8709 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12206.145 | 0.9853 | 0.9662 | 0.8709 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12206.145 | 0.9575 | 0.9028 | 0.8709 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12206.145 | 0.9575 | 0.9028 | 0.8709 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12206.145 | 0.9614 | 0.9117 | 0.8709 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12206.145 | 0.9614 | 0.9117 | 0.8709 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12206.145 | 0.9773 | 0.9480 | 0.8709 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12206.145 | 0.9773 | 0.9480 | 0.8709 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12206.145 | 0.9721 | 0.9360 | 0.8709 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 12206.145 | 0.9721 | 0.9360 | 0.8709 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12206.145 | 0.2103 | -0.6663 | 0.8709 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 12206.145 | 0.2103 | -0.6663 | 0.8709 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12206.145 | 0.0343 | -0.9584 | 0.8709 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 12206.145 | 0.0343 | -0.9584 | 0.8709 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12206.145 | 0.0140 | -0.9851 | 0.8709 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 12206.145 | 0.0140 | -0.9851 | 0.8709 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12206.145 | 0.0158 | -0.9829 | 0.8709 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 12206.145 | 0.0158 | -0.9829 | 0.8709 |