Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14640.189 | 0.9629 | 0.9525 | 1.5721 | |
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14640.189 | 0.9629 | 0.9525 | 1.5721 | |
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14640.189 | 0.9511 | 0.9372 | 1.5721 | |
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14640.189 | 0.9511 | 0.9372 | 1.5721 | |
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14640.189 | 0.9474 | 0.9324 | 1.5721 | |
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14640.189 | 0.9474 | 0.9324 | 1.5721 | |
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14640.189 | 0.5480 | 0.3642 | 1.5721 | |
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14640.189 | 0.5480 | 0.3642 | 1.5721 | |
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14640.189 | 0.2318 | -0.2108 | 1.5721 | |
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14640.189 | 0.2318 | -0.2108 | 1.5721 | |
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14640.189 | 0.0256 | -0.8059 | 1.5721 | |
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14640.189 | 0.0256 | -0.8059 | 1.5721 | |
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14640.189 | 0.0240 | -0.8133 | 1.5721 | |
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14640.189 | 0.0240 | -0.8133 | 1.5721 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10998.145 | 0.9004 | 0.7888 | 0.9403 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10998.145 | 0.9004 | 0.7888 | 0.9403 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10998.145 | 0.9229 | 0.8365 | 0.9403 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10998.145 | 0.9229 | 0.8365 | 0.9403 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10998.145 | 0.8992 | 0.7863 | 0.9403 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10998.145 | 0.8992 | 0.7863 | 0.9403 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10998.145 | 0.9458 | 0.8849 | 0.9403 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10998.145 | 0.9458 | 0.8849 | 0.9403 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10998.145 | 0.8493 | 0.6810 | 0.9403 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10998.145 | 0.8493 | 0.6810 | 0.9403 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10998.145 | 0.2286 | -0.5838 | 0.9403 |