Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF12A | NM | Basal B | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14637.189 | 0.0065 | -0.6884 | 2.7087 | |
| MCF12A | NM | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14637.189 | 0.0051 | -0.7161 | 2.7087 | |
| MCF12A | NM | Basal B | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14637.189 | 0.0051 | -0.7161 | 2.7087 | |
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10997.145 | 0.9586 | 0.9402 | 1.3945 | |
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 10997.145 | 0.9586 | 0.9402 | 1.3945 | |
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10997.145 | 0.8900 | 0.8397 | 1.3945 | |
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 10997.145 | 0.8900 | 0.8397 | 1.3945 | |
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10997.145 | 0.9805 | 0.9719 | 1.3945 | |
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 10997.145 | 0.9805 | 0.9719 | 1.3945 | |
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10997.145 | 1.0218 | 1.0312 | 1.3945 | |
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 10997.145 | 1.0218 | 1.0312 | 1.3945 | |
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10997.145 | 0.8797 | 0.8244 | 1.3945 | |
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 10997.145 | 0.8797 | 0.8244 | 1.3945 | |
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10997.145 | 0.5476 | 0.2986 | 1.3945 | |
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 10997.145 | 0.5476 | 0.2986 | 1.3945 | |
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10997.145 | 0.0853 | -0.6577 | 1.3945 | |
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 10997.145 | 0.0853 | -0.6577 | 1.3945 | |
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10997.145 | 0.0195 | -0.8813 | 1.3945 | |
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 10997.145 | 0.0195 | -0.8813 | 1.3945 | |
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10997.145 | 0.0144 | -0.9042 | 1.3945 | |
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 10997.145 | 0.0144 | -0.9042 | 1.3945 | |
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14640.189 | 0.9866 | 0.9829 | 1.5721 | |
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14640.189 | 0.9866 | 0.9829 | 1.5721 | |
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14640.189 | 0.9894 | 0.9865 | 1.5721 | |
| MCF7 | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14640.189 | 0.9894 | 0.9865 | 1.5721 |