Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14264.189 | 0.9462 | 0.9144 | 1.2647 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 14264.189 | 0.9462 | 0.9144 | 1.2647 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14264.189 | 0.9510 | 0.9221 | 1.2647 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 14264.189 | 0.9510 | 0.9221 | 1.2647 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14264.189 | 0.9494 | 0.9195 | 1.2647 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 14264.189 | 0.9494 | 0.9195 | 1.2647 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14264.189 | 0.9595 | 0.9357 | 1.2647 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 14264.189 | 0.9595 | 0.9357 | 1.2647 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14264.189 | 0.9531 | 0.9255 | 1.2647 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.107 | uM | 14264.189 | 0.9531 | 0.9255 | 1.2647 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14264.189 | 0.1148 | -0.6388 | 1.2647 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 0.533 | uM | 14264.189 | 0.1148 | -0.6388 | 1.2647 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14264.189 | 0.0100 | -0.9475 | 1.2647 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 2.67 | uM | 14264.189 | 0.0100 | -0.9475 | 1.2647 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14264.189 | 0.0142 | -0.9307 | 1.2647 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 13.3 | uM | 14264.189 | 0.0142 | -0.9307 | 1.2647 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14264.189 | 0.4218 | 0.0107 | 1.2647 | |
| MDA-MB-134-VI | HR+ | Luminal | MG-132 | Proteasome | Proteasome | 66.7 | uM | 14264.189 | 0.4218 | 0.0107 | 1.2647 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12594.17 | 1.0258 | 1.0423 | 1.2180 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000171 | uM | 12594.17 | 1.0258 | 1.0423 | 1.2180 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12594.17 | 0.9771 | 0.9623 | 1.2180 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.000853 | uM | 12594.17 | 0.9771 | 0.9623 | 1.2180 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12594.17 | 1.0313 | 1.0512 | 1.2180 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.00427 | uM | 12594.17 | 1.0313 | 1.0512 | 1.2180 | |
| MDA-MB-157 | TNBC | Basal B | MG-132 | Proteasome | Proteasome | 0.0213 | uM | 12594.17 | 1.0136 | 1.0223 | 1.2180 |